computational biology

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

BioCompute Objects provide a structured language and format for sharing computational protocols and procedures for next-generation sequencing data with regulatory agencies.

A study of gene expression data from 173 breast cancer patients identified subtype-specific associations between molecular processes in tumor and blood cells. 

Enpicom will initially offer separate solutions on its ImmunoGenomiX platform for research and clinical applications in oncology but seeks to expand into other disease areas.

In Genome Research this week: sex-biased gene expression evolution in malaria mosquitos, method to find ancient selective sweeps, and more.

The software, developed by researchers at the Ontario Institute for Cancer Research, uses machine learning methods to classify mutations as germline or somatic.

Participants tried to classify samples based on the epigenomic impact of cigarette smoke cessation and aerosol from modified- or reduced-risk products.

The computational method, called DeepCpG, is designed to tease out missing epigenetic marks and related DNA motifs in single-cell DNA methylation data.

Codexis has been using its CodeEvolver platform to engineer high-performance enzymes for next-generation sequencing and PCR for in vitro diagnostics.

Objectives for this year include building a network of ELIXIR beacons, developing new features and security measures, and partnering with data owners.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.