computational biology

VC firm Andreessen Horowitz is putting big money into its second biology-focused investment fund in hopes of supporting engineering approaches to science.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

BioCompute Objects provide a structured language and format for sharing computational protocols and procedures for next-generation sequencing data with regulatory agencies.

A study of gene expression data from 173 breast cancer patients identified subtype-specific associations between molecular processes in tumor and blood cells. 

Enpicom will initially offer separate solutions on its ImmunoGenomiX platform for research and clinical applications in oncology but seeks to expand into other disease areas.

In Genome Research this week: sex-biased gene expression evolution in malaria mosquitos, method to find ancient selective sweeps, and more.

The software, developed by researchers at the Ontario Institute for Cancer Research, uses machine learning methods to classify mutations as germline or somatic.

Participants tried to classify samples based on the epigenomic impact of cigarette smoke cessation and aerosol from modified- or reduced-risk products.

The computational method, called DeepCpG, is designed to tease out missing epigenetic marks and related DNA motifs in single-cell DNA methylation data.

Codexis has been using its CodeEvolver platform to engineer high-performance enzymes for next-generation sequencing and PCR for in vitro diagnostics.

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In a survey, about half of Canadian government scientists say they still feel as though they cannot speak freely, ScienceInsider reports.

The Atlantic reports that biohacker Josiah Zayner regrets injecting himself with the CRISPR gene-editing tool on stage.

Clinicians in China are moving ahead with a number of CRISPR trials, NPR reports, as the US embarks on its first.

In Nature this week: genomic approaches applied to study Neolithic and Bronze Age Europeans, and more.