computational biology
Human Population Nearly Went Extinct 900,000 Years Ago, Genetic Study Suggests
Using genomic data from present-day humans and a new analytical approach, investigators found a population bottleneck that resulted in fewer than 1,300 breeding individuals.
In a keynote address at ISMB-ECCB, Dana Pe'er reviewed the development of single-cell analysis techniques that have been 20 years in the making.
Schizophrenia Ties to Mosaic CNVs Suggest Early Developmental Origins of the Disease
Analyzing case-control genotyping profiles, researchers saw somatic copy number changes recurring in two genes in individuals with schizophrenia.
One Biosciences Using Single-Cell Transcriptomics to Understand Cancer Therapy Response, Resistance
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The Institut Curie spinout recently published its single-cell data mining method, which it is applying to collaborations with hospitals and pharmaceuticals.
Pluto Biosciences Closes $3.7M Seed Funding Round
This is the second funding round for Pluto, a Wyss Institute spinout that has developed a collaborative platform for genome analysis workflows.