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comparative genomics

To understand the evolution of brain conditions and other traits, investigators plan to sequence human and pathogen DNA in thousands of samples from Europe.

Using genome sequences for 161 present-day Papuans and Island Southeast Asians, researchers described three Denisovan lineages and estimated divergence times between them.

Multi-drug resistant Enterococcus faecalis isolates from a Wisconsin hospital contained independent mutations falling at overlapping resistance-related loci.

Researchers found a potential alternative toxin, as well as antibiotic resistance genes, in a newly-sequenced Vibrio cholerae strain from a British WWI soldier.

Researchers retraced transmission events and resistance contributors with whole-genome sequences for 100 carbapenem-resistant Klebsiella pneumoniae isolates from a Beijing hospital.

Researchers assembled a near chromosome-level genome for the cultivated octoploid strawberry, uncovering the plant's diploid progenitors and sub-genome interactions.

Using sequences from a 4,900-year-old Swedish gravesite, researchers identified a pathogenic form of Yersinia pestis circulating in Europe during the Neolithic Period.

Using newly sequenced and existing plague genomes, researchers saw signs that the Second Plague Pandemic may have involved multiple introductions to Europe.

With sequence data for 910 African individuals, researchers found more than 296 million bases of sequence not represented in the human reference genome GRCh38.

Researchers identified gene family expansions and other parasitic adaptations using genome sequences for 81 roundworms or flatworms.

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The New York Times Magazine examines gender discrimination at the Salk Institute.

Science reports that MD Anderson Cancer Center has dismissed three researchers over foreign tie concerns.

A second death in gene therapy trial for type 1 spinal muscular atrophy is under investigation, according to Reuters.

In PLOS this week: antibiotic resistance patterns in Escherichia coli, a dozen genetic loci tied to varicose vein risk, and more.