comparative genomics

Wild jaguar

With new and available genome sequences, investigators delved into phylogenetic patterns and adaptations in lions, leopards, tigers, snow leopards, and jaguars.

Researchers saw an over-representation of rarer variants in isolated groups when they sequenced thousands of individuals from 10 European populations.

Following treated leprosy patients, researchers saw three cases of recurrence that were classified as re-infection or relapse cases with genome sequences.

Copy number alterations in red blood cell invasion receptor-related genes that are more common in some African populations appear to protect against severe malaria.

This Week in PNAS

In PNAS this week: SERPINA1 gene variant linked to stroke risk, comparative genomic analysis of cyanobacteria, and more.

Snakehead (Channa argus).

The genome may serve as a resource for those studying the fish, which is economically important in some parts of the world and an invasive species in others. 

In Genome Biology this week: comparative genomics study of Aspergillus, genetic variation in indigenous African cattle, and more.

The transition from hunter-gatherer to agricultural lifestyles seems to have spread to the Baltics without massive migration from Anatolia or the Levant.

An international team sequenced samples from two 8,000-year-old human skeletons and compared them to other ancient and modern sequences.

The new sequences also uncovered two new gene families likely involved in Plasmodium malariae's ability to invade host cells.

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Researchers find that a personalized medicine approach could help people who experience pain while taking statins, New Scientist reports.

US National Science Foundation is continuing its responsible research conduct training policy despite its flaws, ScienceInsider reports.

A CRISPR-themed meeting explored how the tool could and should be used, Wired reports.

In Science this week: database of proteins' effects on cancer, targeted error correction sequencing, and more.