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comparative genomics

Researchers compared schizophrenia genetic risk loci in individuals from East Asian and European populations, uncovering many shared features.

Mitochondrial sequences suggest some haplogroups found in Finland today arrived in the region pre-Iron Age, though population distributions have shifted.

Researchers uncovered examples of potentially beneficial copy number variants introgressed from Neanderthals and Denisovans under positive selection in Melanesians.

Researchers identified Streptococcus pyogenes isolates from a lineage dubbed M1UK that are predicted to produce higher-than-usual levels of a scarlet fever-associated toxin.

An analysis of more than 900 C. difficile isolates uncovered four phylogenetic lineages, including three lineages in a clade showing recent positive selection on infection-related genes.

Researchers analyzed more than 550 new and previously sequenced exomes for individuals from African rainforest hunter-gatherer and farming populations, searching for local adaptations.

With whole-genome sequences and other analyses, researchers delved into drug resistance and more in 600 staphylococcus isolates from high-touch surfaces in East and West London.

Researchers used exome sequences on almost 550 canine transmissible venereal tumors to estimate their origin, global spread, and evolution.

Re-expression of DUX4, which is normally silenced in somatic tissues, appeared to stymie MHC class I-related immune activity in several solid cancer types.

By sequencing 10 Bronze, early Iron, and late Iron Age individuals, researchers retraced ancestry patterns at a Philistine port city in present-day Israel.

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Forensic genetic firm Verogen has bought the genetic genealogy site GEDmatch.

Researchers have 3D-printed plastic bunnies that encase the information needed to make more such bunnies in DNA, according to Discover magazine.

Dan Rather, the former CBS Evening News anchor and executive producer of a new documentary, writes at the Guardian that everyone needs to know about CRISPR.

In PNAS this week: analysis of FOXA1 upregulation in ER-positive breast cancer, gene editing to correct recessive dystrophic epidermolysis bullosa, and more.