An analysis of more than 900 C. difficile isolates uncovered four phylogenetic lineages, including three lineages in a clade showing recent positive selection on infection-related genes.
Researchers analyzed more than 550 new and previously sequenced exomes for individuals from African rainforest hunter-gatherer and farming populations, searching for local adaptations.
With whole-genome sequences and other analyses, researchers delved into drug resistance and more in 600 staphylococcus isolates from high-touch surfaces in East and West London.
Re-expression of DUX4, which is normally silenced in somatic tissues, appeared to stymie MHC class I-related immune activity in several solid cancer types.
By sequencing 10 Bronze, early Iron, and late Iron Age individuals, researchers retraced ancestry patterns at a Philistine port city in present-day Israel.
By analyzing thousands of cancer genomes, investigators identified hotspots for passenger mutations at DNA hairpin sites that are a preferred substrate for APOBEC, a cytidine deaminase.
Despite the diversity detected in Group A Streptococcus strains from more than 20 countries, investigators narrowed in on broadly shared sequences with relatively low variation.
Researchers identified 34 known and 30 new Leptospira species by sequencing dozens of isolates from soil and water samples in Asia, Africa, Europe, and Oceania.
Genetic material found in tooth samples from the Bronze Age, Iron Age, and Medieval period points to migrations from Siberia at the Bronze Age-Iron Age transition.
A genetic analysis of salmon scales collected over the course of a century points to a sharp decline in the number of fish returning each year to river in British Columbia, CBC reports.
