comparative genomics Sequencing Study Uncovers Genes Under Positive Selection in Large, Long-Lived Sea Creatures Sequences from a range of cetacean species suggest the aquatic environment has exerted selective pressure genes involved in growth, cancer suppression, and other features. Boost to Modern Human Brain Linked to Single Amino Acid Substitution A modern human-specific lysine-to-arginine substitution in transketolase-like 1 led to enhanced neuron cell levels and neuroprogenitor representation in the brain's frontal neocortex. Ancient Wolf Genomes Reveal Ice Age Population Connections, Clues to Origins of Dogs Based on dozens of ancient wolf genomes, researchers detected genetic connectedness during the Ice Age and proposed at least two wolf sources of dog domestication. Octopus, Squid Genome Assemblies Reveal Hallmarks of Cephalopod Evolution Researchers detected genome shuffling, gene expansions, and RNA editing changes in the cephalopod lineage using genome assemblies for three representatives. Unique Fraction of Modern Human Genome Surprisingly Small, Comparison With Archaic Hominins Suggests Human-specific sequences not found in Neanderthals or Denisovans appeared to make up 1.5 to 7 percent of the human genome, contributing to brain-related processes. Apr 9, 2021 Enterobacteriaceae Pangenomes Offer Look at Antimicrobial Resistance Reservoirs in Natural Populations Apr 7, 2021 Ancient Sequencing Studies Provide Look at Early Modern Human Populations in Europe Oct 29, 2020 Dozens of Introduction Events Sparked SARS-CoV-2 Spread in Oregon, Sequence Data Suggests Premium Oct 21, 2020 Gut Microbiome Analysis in Autistic Children Points to Detoxification Deficiencies Sep 16, 2020 Ancient DNA Study Argues Against Horses Domesticated in Anatolia Sep 11, 2020 Genomic Epidemiology Studies Retrace Sources of Early SARS-CoV-2 Outbreaks in US, Europe Aug 20, 2020 Annotation Analysis Looks at Variants in SARS-CoV-2 Genomes From First Phase of Pandemic Jul 28, 2020 SARS-CoV-2 Lineage May Go Back 'Decades' in Bats, Phylogenetic Analysis Suggests Jul 28, 2020 Neanderthals Reintroduced Alleles from Common Ancestor to Modern Humans Jul 21, 2020 Inflammatory Bowel Disease Study Points to Role For Somatic Colon Mutations Jun 11, 2020 Coronavirus Pathogenicity Clues Uncovered Using Machine-Learning Approach Jun 1, 2020 SARS-CoV-2 Result of Bat, Pangolin Virus Recombination, Purifying Selection, Study Suggests May 14, 2020 Historical East Asian Population Relationships, Migrations Proposed From Ancient Sequences May 8, 2020 Pangolin Coronavirus Analysis Finds High Similarity to SARS-CoV-2 Apr 30, 2020 Treatment Clues Gleaned From Molecular Features in Rare Kidney Cancer Type Apr 20, 2020 Neolithic, Bronze Age Population Dynamics Drawn From Ancient Central European Genomes Apr 13, 2020 SARS-CoV-2 Genomes Let Researchers Retrace Viral Spread, Mitigation Effects Mar 25, 2020 Prostate Cancer Cases in China Show Recurrent Alterations Distinct From Western Cohorts Mar 18, 2020 SARS-CoV-2 not Man-Made, Comparative Genomic Study Concludes Feb 24, 2020 Ancient Salmonella Genomes Reveal Human Lifestyle-Related Host Adaptations Load More Breaking News New Products Posted to GenomeWeb: Qiagen, Thermo Fisher, Bionano Genomics, BillionToOne, More People in the News at Illumina Ventures, Element Biosciences, Epigenomics, Exagen, More Genomic Approaches Boost Rare Disease Diagnoses in Middle Eastern Patient Population GeneDx to Raise $150M in Public and Direct Stock Offerings In Brief This Week: T2 Biosystems, Novacyt, OpGen, Dante Genomics, Nautilus Biotechnology, More The Scan Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups. Genome-Wide Analysis Sheds Light on Genetics of ADHD A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder. MicroRNA Cotargeting Linked to Lupus A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus. Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.