comparative genomics

Using sequences from a 4,900-year-old Swedish gravesite, researchers identified a pathogenic form of Yersinia pestis circulating in Europe during the Neolithic Period.

Using newly sequenced and existing plague genomes, researchers saw signs that the Second Plague Pandemic may have involved multiple introductions to Europe.

With sequence data for 910 African individuals, researchers found more than 296 million bases of sequence not represented in the human reference genome GRCh38.

Researchers identified gene family expansions and other parasitic adaptations using genome sequences for 81 roundworms or flatworms.

Researchers developed a k-mer-based classification scheme to assay lncRNA function, identifying cis-repressive lncRNAs with k-mer features resembling Xist.

After a series of duplication and rearrangement events, the genes involved in two key pathways producing morphine, codeine, and noscapine have clustered in the genome.

Brown bear.

By sequencing four ancient cave bears and comparing them to other bear species, researchers retraced historical admixture of cave bears and brown bears.

Diet- and height-related variants were selected for in a Flores Island pygmy population, according to a study, which also provided insights into the population's history.

When researchers sequenced some 800 global Staphylococcus aureus isolates, they saw signs of previous jumps from humans to domestic animals and beyond.

A new deep neural network approach used common variants in non-human primate genomes to distinguish between benign variants and those involved in human disease.

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Germany's Project DEAL has come to an agreement with the publisher Wiley over journal access and open-access publishing, ScienceInsider reports.

Researchers uncover additional loci associated with lifespan, which the Telegraph says could be folded into a genetic test.

A Canadian panel recommends public coverage of the gene therapy Kymriah if its cost comes down, the Globe and Mail reports.

In Nucleic Acids Research this week: new accurate quantification by sequencing approach, CNV breakpoints in Plasmodium falciparum, and more.