comparative genomics
Unique Fraction of Modern Human Genome Surprisingly Small, Comparison With Archaic Hominins Suggests
Human-specific sequences not found in Neanderthals or Denisovans appeared to make up 1.5 to 7 percent of the human genome, contributing to brain-related processes.
Enterobacteriaceae Pangenomes Offer Look at Antimicrobial Resistance Reservoirs in Natural Populations
Sequence data on more than 800 farm or wastewater Enterobacteriaceae isolates suggested pangenome dynamics may be influenced by geography and environmental niches.
Ancient Sequencing Studies Provide Look at Early Modern Human Populations in Europe
A pair of new studies focus on two modern human populations with recent Neanderthal mixing that lived in Europe around 45,000 or more years ago.
At the ASHG conference, a researcher described efforts to sequence SARS-CoV-2 genomes from Oregon to investigate introductions, super-spreader events, and viral biology.
Gut Microbiome Analysis in Autistic Children Points to Detoxification Deficiencies
A quasi-paired cohort analysis identified shifts in the detoxifying function of gut microbes from individuals with autism spectrum disorder.