comparative genomics Unique Fraction of Modern Human Genome Surprisingly Small, Comparison With Archaic Hominins Suggests Human-specific sequences not found in Neanderthals or Denisovans appeared to make up 1.5 to 7 percent of the human genome, contributing to brain-related processes. Enterobacteriaceae Pangenomes Offer Look at Antimicrobial Resistance Reservoirs in Natural Populations Sequence data on more than 800 farm or wastewater Enterobacteriaceae isolates suggested pangenome dynamics may be influenced by geography and environmental niches. Ancient Sequencing Studies Provide Look at Early Modern Human Populations in Europe A pair of new studies focus on two modern human populations with recent Neanderthal mixing that lived in Europe around 45,000 or more years ago. Dozens of Introduction Events Sparked SARS-CoV-2 Spread in Oregon, Sequence Data Suggests Premium At the ASHG conference, a researcher described efforts to sequence SARS-CoV-2 genomes from Oregon to investigate introductions, super-spreader events, and viral biology. Gut Microbiome Analysis in Autistic Children Points to Detoxification Deficiencies A quasi-paired cohort analysis identified shifts in the detoxifying function of gut microbes from individuals with autism spectrum disorder. Sep 16, 2020 Ancient DNA Study Argues Against Horses Domesticated in Anatolia Sep 11, 2020 Genomic Epidemiology Studies Retrace Sources of Early SARS-CoV-2 Outbreaks in US, Europe Aug 20, 2020 Annotation Analysis Looks at Variants in SARS-CoV-2 Genomes From First Phase of Pandemic Jul 28, 2020 SARS-CoV-2 Lineage May Go Back 'Decades' in Bats, Phylogenetic Analysis Suggests Jul 28, 2020 Neanderthals Reintroduced Alleles from Common Ancestor to Modern Humans Jul 21, 2020 Inflammatory Bowel Disease Study Points to Role For Somatic Colon Mutations Jun 11, 2020 Coronavirus Pathogenicity Clues Uncovered Using Machine-Learning Approach Jun 1, 2020 SARS-CoV-2 Result of Bat, Pangolin Virus Recombination, Purifying Selection, Study Suggests May 14, 2020 Historical East Asian Population Relationships, Migrations Proposed From Ancient Sequences May 8, 2020 Pangolin Coronavirus Analysis Finds High Similarity to SARS-CoV-2 Apr 30, 2020 Treatment Clues Gleaned From Molecular Features in Rare Kidney Cancer Type Apr 20, 2020 Neolithic, Bronze Age Population Dynamics Drawn From Ancient Central European Genomes Apr 13, 2020 SARS-CoV-2 Genomes Let Researchers Retrace Viral Spread, Mitigation Effects Mar 25, 2020 Prostate Cancer Cases in China Show Recurrent Alterations Distinct From Western Cohorts Mar 18, 2020 SARS-CoV-2 not Man-Made, Comparative Genomic Study Concludes Feb 24, 2020 Ancient Salmonella Genomes Reveal Human Lifestyle-Related Host Adaptations Jan 13, 2020 Aging Markers, Patterns Found in Longitudinal Multi-Omics Study Nov 18, 2019 Schizophrenia Loci Overlap in East Asians, Europeans but Polygenic Risk Scores Don't Transfer Well Nov 15, 2019 Ancient Mitochondrial Genomes Reveal Longstanding Lineages in Finland Oct 17, 2019 Selection Analysis Suggests Modern Melanesians Carry Adaptive Archaic Hominin CNVs Load More Breaking News Pediatric Cardiomyopathy Exome Sequencing Study Suggests More Disease Genes to be Found People in the News: New Appointments at Helix, Pacific Biosciences, SomaLogic, More New Products Posted to GenomeWeb: Amoy Diagnostics, Akoya Biosciences, Congenica, Lucence In Brief This Week: BGI, Gencove, Cepheid, Biocartis, Biognosys, Co-Diagnostics, More Florida Lab Owner Pleads Guilty to $6.9M COVID-19 False Billing Scheme Pacific Biosciences Outlines Progress on Short-Read Sequencing at JPM, Partners With Canexia Health The Scan Close Panel Vote on Califf Nomination The New York Times reports there was a close committee vote to advance the nomination of Robert Califf to lead the US Food and Drug Administration to the full Senate. Task Force Reports on Scientific Integrity Nature News writes that that a new task force report recommends that the US establish a cross-agency scientific integrity council. Across the Hall Genetic testing, closed-circuit cameras, and more show how a traveler, without any contact, infected others at a New Zealand quarantine facility, CNN reports. Science Paper Examines Influence of Chromatin Modifications on Obsessive-Compulsive Disorder In Science this week: genes regulating chromatin modification may contribute to OCD risk.