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comparative genomics

A comparative genomics and machine-learning analysis spanning almost 1,000 viral genomes pointed to two proteins that appear to be altered in SARS-CoV-2 and MERS-CoV.

In Genome Research this week: gene expression in primate brain regions, inversions and breakpoint inverted repeats in the human genome, and more.

The ancestor of a bat coronavirus may have obtained a receptor binding motif found among pangolin coronaviruses through a recombination event.

Ancient sequences from two-dozen individuals revealed genetically distinct populations from northern and southern East Asia that ultimately met and mixed.

SARS-CoV-2 might have resulted from recombination between pangolin and bat coronaviruses, with pangolins serving as an intermediate host.

Integrated analyses uncovered recurrent changes in renal medullary carcinoma, including potential treatment vulnerabilities stemming from DNA replication stress.

Researchers described ancestry patterns, apparent population interactions, and genetic turnover during the late Neolithic and early Bronze Age.

Researchers have been using Nextstrain, which includes data for thousands of SARS-CoV-2 genomes, to study how the virus accrues mutations over time.

An integrated analysis involving prostate cancer patients from China highlighted frequent FOXA1 mutations and deletions in two other genes.

Though it is unclear whether the virus became pathogenic before or after the jump from animals to humans, genomic features point to a natural source for the COVID-19 coronavirus.

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The Washington Post reports on researchers' efforts to determine the effect of an increasingly common SARS-CoV-2 mutation.

Florida Politics reports Florida's law barring life, long-term care, and disability insurers from using genetic information in coverage decisions went into effect at the beginning of July.

A new analysis finds a link between popular media coverage of a scientific study and how often that paper is cited.

In Nature this week: CRISPR approaches to editing plant genomes, way to speed up DNA-PAINT, and more.