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comparative genomics

At the ASHG conference, a researcher described efforts to sequence SARS-CoV-2 genomes from Oregon to investigate introductions, super-spreader events, and viral biology.

A quasi-paired cohort analysis identified shifts in the detoxifying function of gut microbes from individuals with autism spectrum disorder.

Researchers characterized more than 100 ancient equid samples stretching over some 9,000 years, spanning the early Neolithic Age to the Iron Age.

By combining genome sequence data with phylogenetics and other clues, two teams looked at the SARS-CoV-2 introductions that sparked outbreaks in North America and Europe.

In Cell this week: systems biology analysis of inflammatory syndrome seen in children with COVID-19, single-cell RNA-sequencing strategies, and more.

Using sequence data from nearly 2,500 isolates submitted to GISAID before April, researchers tallied coding and non-coding changes in the virus across locations and conditions.

Gene length is associated with lifespan in a comparative genomics study appearing in the Proceedings of the National Academy of Sciences that draws on the whale shark genome.

With genome sequence alignments and phylogenetic analyses focused on non-recombining regions, researchers traced the SARS-CoV-2 lineage in bats back at least 40 years.

Ancestral alleles "reintroduced" by Neanderthal admixture are prone to functional in the human genome, based on an analysis of East Asian, South Asian, and European sequences.

Analyzing genome sequences from dozens of cases and controls, researchers saw an IBD-associated jump in somatic mutations in colonic crypt samples.

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Imperial College London researchers are shifting away from testing a COVID-19 vaccine to focus on combating newly emerging SARS-CoV-2 variants, the Independent says.

According to the Associated Press, genetic genealogy has helped law enforcement officials identify an unknown victim of the Green River Killer.

In PNAS this week: target to reduce chemotherapy-induced cardiac injury, tool finds ancient endogenous RNA viruses, and more.

Moderna reports its vaccine is effective against new SARS-CoV-2 strains, though it is also developing a booster, according to the New York Times.