Researchers used genomic approaches to delve into the cleft lip and palate-related functions of a transcription factor called p63, identifying key enhancer and chromatin interactions.
A structural variant analysis based on genome sequences for almost 800 multiple myeloma cases suggests a IgL translocation present in nearly 10 percent of patients may inform survival.
With single-cell genome sequencing, recombination assays, and other approaches in mouse cells, researchers identified factors affecting DNA crossover.
Researchers prioritized schizophrenia risk SNPs from genome-wide association studies and used functional genomics to find transcription factor-disrupting risk SNPs.
A multi-omic analysis implicated a handful of transcription factors, along with genes and regulatory RNAs down- and upstream of them, in metastatic colorectal cancer.
In a set of new studies, members of an international team mapped gene variation, expression, and regulatory interactions in developing and adult human brains.
The companies have agreed to offer OnRamp Bioinformatics' genomic data analysis platform with Active Motif's epigenetics research kits.
Researchers found that methylation alterations affected immune response and lipid metabolism pathways in children whose growth had been stunted.
The researchers found that genes whose transcription in response to an immune challenge diverged across species also varied between single cells.
A group led by St. Jude Children's Research Hospital integrated transcriptomic, epigenomic, proteomic, and phoshoproteomic data.
The US Patent and Trademark Office is opening another interference proceeding in the CRISPR patent fight.
There's increasing genetic evidence that a number of ancient hominins may have contributed to the human gene pool, according to Discover's The Crux blog.
The Japan News writes that Japan needs to seize the opportunity to ensure that a wide number of people benefit from personalized cancer treatments.
In Cell this week: messenger RNA expression and translation, RNA localization atlas, and more.