ChIP-seq

A multi-omic analysis implicated a handful of transcription factors, along with genes and regulatory RNAs down- and upstream of them, in metastatic colorectal cancer.

In a set of new studies, members of an international team mapped gene variation, expression, and regulatory interactions in developing and adult human brains.

The companies have agreed to offer OnRamp Bioinformatics' genomic data analysis platform with Active Motif's epigenetics research kits.

Researchers found that methylation alterations affected immune response and lipid metabolism pathways in children whose growth had been stunted.

The researchers found that genes whose transcription in response to an immune challenge diverged across species also varied between single cells.

A group led by St. Jude Children's Research Hospital integrated transcriptomic, epigenomic, proteomic, and phoshoproteomic data.

This Week in PNAS

In PNAS this week: retrotransposon expression and regulation in human cells, convergent evolution in photoreceptor proteins, and more.

While digging into the tumor-suppressive mechanism for an X-linked gene called UTX, researchers found a similar protective role for the Y chromosome gene UTY.

The SurfaceChIP-seq method enables inputs down to 30 cells as well as the ability to analyze multiple histone modifications in parallel.

Cincinnati Children's Hospital Medical Center researchers found that disease risk loci overlap with transcription factor binding sites.

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Researchers are refining a tool to predict a woman's risk of developing breast cancer, according to the Guardian.

According to Stat News, the partial government shutdown in the US could soon affect the ability of the Food and Drug Administration to review new drugs.

In PNAS this week: gypsy moth genome sequenced, phylogenomic analysis of Polyneopterans, and more.

CNN reports that people's genes tend to have a greater influence on their risk of developing disease than their environment, but it varies by phenotype.