ChIP-seq
Ankylosing Spondylitis Genomics Study Points to Genes, Pathways for Drug Discovery
Researchers analyzed transcriptomic and epigenomic features in immune cells from cases and controls alongside genetic risk data.
New Resource Combines Functional Genomics, Diploid Genomes for Variant Annotation
Coupling high-quality, long-read genomes with functional assays, researchers tracked the effects of genetic variants across dozens of tissue types in four individuals.
Glioblastoma With Wild-Type TP53 Linked to Potentially Targetable Epigenetic Alteration
With the help of a CRISPR-based screen, researchers linked enhanced activity by the chromatin regulatory gene BRD8 to altered p53 function in cells containing wild-type TP53.
Liver Cancer Detection Score Developed With Machine Learning Analysis of Blood Plasma DNA Fragments
Researchers used machine learning to come up with a cell-free DNA 'fragmentome'-based score for finding hepatocellular carcinoma cases from blood plasma samples.
Studies Unravel SARS-CoV-2 Protein Interactions With Human Proteins
A pair of studies identified connections between proteins from SARS-CoV-2 and human cells, hitting on key host pathways and potential treatment targets.