ChIP-seq Blood Cancer Genetic Risk Loci Found in Retriever Dogs Using a genome-wide association study and multiomic follow up, investigators tracked down genes involved in histiocytic sarcoma in flat-coated retrievers. Alzheimer's Disease Linked to Epigenetic Changes in Multi-Omic Study Investigators identified disease-associated histone modifications in the brain that appeared to influence transcription- and chromatin-related processes. ENCODE Phase Three Offers New Insights Into Genomic Regulatory Regions, Organization In more than a dozen new papers, ENCODE researchers reported on analyses of the human and mouse genomes, using new data types and additional tissues. Prostate Cancer Metastasis Linked to Development-Related Epigenetic Shift Transcription factor reprogramming during prostate cancer metastases appears to involve epigenetic changes that resemble those at play during prostate development, new research finds. Extrachromosomal Oncogene Amplification Involves Rearrangement of Regulatory Elements Functional enhancers can accompany oncogenes on the circularized extrachromosomal amplicons found in glioma and other tumors, enhancing cancer growth. May 1, 2019 Cleft Palate Study Shows Transcription Factor, Enhancer Roles in Related Developmental Processes Apr 24, 2019 Multiple Myeloma Sequences Reveal Prognostic Immunoglobulin Translocation Mar 22, 2019 Single-Cell Sperm Sequencing Reveals New Details About Recombination Feb 8, 2019 Schizophrenia Regulatory Mechanisms Revealed by Risk SNP Functional Analysis Dec 14, 2018 Metastatic Colorectal Cancer Linked to Transcription Factors, Gene Networks Dec 13, 2018 PsychENCODE Studies Explore Brain Development, Neuropsychiatric Regulatory Features Dec 13, 2018 OnRamp, Active Motif Ink Epigenetic Data Analysis Partnership Nov 12, 2018 DNA Methylation Changes Uncovered in Undernourished Children Oct 25, 2018 Innate Immunity Differs Across Species and Cells, Gene Expression Study Finds Aug 23, 2018 Multi-Omic Analysis of Rhabdomyosarcoma Points to Drug Targets in Deregulated Pathways May 7, 2018 Acute Myeloid Leukemia Protection Provided by Y Chromosome Gene Apr 19, 2018 Virginia Tech Team Develops Microfluidic Technique for Low-Input ChIP-seq Premium Apr 16, 2018 Epstein-Barr Virus Protein, Human Transcription Factors Implicated in Autoimmune Diseases Apr 5, 2018 Research Groups Seek Biomarkers of Asthma Drug Resistance in Populations With African Ancestry Premium Mar 27, 2018 Aggressive Meningioma Linked to Transcription Factor Activity Mar 5, 2018 Postmortem Analyses Point to Distinct Epigenetic Features in Aging Alzheimer's Brains Dec 20, 2017 Ependymoma Brain Tumor Enhancers Identified Aug 7, 2017 Regulatory Features of Fusion-Containing Prostate Tumors Hint at Potential Treatment Strategy May 4, 2017 Retina Development, Retinoblastoma Regulation Revealed in Pediatric Cancer Genome Project Paper Nov 18, 2016 Cancer Epigenomic Insights Reported by International Consortia Members Load More Breaking News Alzheimer's Disease Phosphoproteomics Study Uncovers Signaling Abnormalities Genetic Analysis of H. Pylori Indicates Americas Colonized in One Main Migration Event BillionToOne Raises $55M in Series B Financing GeninCode to Launch Cardiovascular Disease Risk Tests in US With Eversana Top Five Articles on GenomeWeb Last Week: Illumina, Liquid Biopsy, Thermo Fisher Scientific, and More Becton Dickinson Sues Beckman Coulter Over Cell Analysis, Sorting IP The Scan Another Resignation According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug. Novavax Finds Its Vaccine Effective Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19. Can't Be Used The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports. PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.