ChIP-seq
Blood Cancer Genetic Risk Loci Found in Retriever Dogs
Using a genome-wide association study and multiomic follow up, investigators tracked down genes involved in histiocytic sarcoma in flat-coated retrievers.
Alzheimer's Disease Linked to Epigenetic Changes in Multi-Omic Study
Investigators identified disease-associated histone modifications in the brain that appeared to influence transcription- and chromatin-related processes.
ENCODE Phase Three Offers New Insights Into Genomic Regulatory Regions, Organization
In more than a dozen new papers, ENCODE researchers reported on analyses of the human and mouse genomes, using new data types and additional tissues.
Prostate Cancer Metastasis Linked to Development-Related Epigenetic Shift
Transcription factor reprogramming during prostate cancer metastases appears to involve epigenetic changes that resemble those at play during prostate development, new research finds.
Extrachromosomal Oncogene Amplification Involves Rearrangement of Regulatory Elements
Functional enhancers can accompany oncogenes on the circularized extrachromosomal amplicons found in glioma and other tumors, enhancing cancer growth.