ChIP-seq

Researchers found that methylation alterations affected immune response and lipid metabolism pathways in children whose growth had been stunted.

The researchers found that genes whose transcription in response to an immune challenge diverged across species also varied between single cells.

A group led by St. Jude Children's Research Hospital integrated transcriptomic, epigenomic, proteomic, and phoshoproteomic data.

This Week in PNAS

In PNAS this week: retrotransposon expression and regulation in human cells, convergent evolution in photoreceptor proteins, and more.

While digging into the tumor-suppressive mechanism for an X-linked gene called UTX, researchers found a similar protective role for the Y chromosome gene UTY.

The SurfaceChIP-seq method enables inputs down to 30 cells as well as the ability to analyze multiple histone modifications in parallel.

Cincinnati Children's Hospital Medical Center researchers found that disease risk loci overlap with transcription factor binding sites.

CU Denver and UC San Francisco teams are independently performing whole-genome sequencing to find genes involved in reduced efficacy of a common bronchodilator drug.

The transcription factor FOXM1 marked meningioma cases with poorer outcomes and enhanced cell proliferation, based on integrated exome, expression, and epigenetic profiles.

This Week in PNAS

In PNAS this week: genetic diversity of MERS in African camels, centromere evolution in Cryptococcus, and more.

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Hundreds of scientists have signed a letter criticizing the open-access Plan S, ScienceInsider reports.

NPR speaks with Rep. Eddie Bernice Johnson (D-Texas) about the US House of Representatives science committee.

A start-up company aiming to match cancer patients to treatments closes after about six weeks, Stat News reports.

In PLOS this week: somatic mutation associations unearthed in thousands of cancer exomes, pathogen detection assay, and more.