ChIP-seq
Genetic Contributors to Ovarian Cancer Subtypes Uncovered in Integrated Genomic Study
Researchers unearthed new and known risk loci for ovarian cancer and ovarian cancer histotypes, and found new candidate causal variants and risk genes.
Cancer May Arise From Epigenetic Changes, Study in Fruit Flies Suggests
Researchers linked transient knockdown of a Polycomb complex component with cancer development and irreversible gene expression changes in developing Drosophila larvae.
Germline Mutagenesis Traced Back to Meiotic Breaks, Error-Prone Repair
By mapping mutations in relation to recombination hotspots, researchers revealed mutagenic effects of meiotic DNA breaks and error-prone repair mechanisms.
Study Examines Cross-Species Sex-Biased Expression at Gene, Organ Levels
Researchers traced sex-biased gene expression patterns across different developmental stages in five organ types from half a dozen species.
Nasopharyngeal Carcinoma Risk Genes Identified, Characterized
Using association, regulatory, and functional analyses coupled with cell line experiments, researchers characterized new nasopharyngeal cancer risk genes.