ChIP-seq

A group led by St. Jude Children's Research Hospital integrated transcriptomic, epigenomic, proteomic, and phoshoproteomic data.

This Week in PNAS

In PNAS this week: retrotransposon expression and regulation in human cells, convergent evolution in photoreceptor proteins, and more.

While digging into the tumor-suppressive mechanism for an X-linked gene called UTX, researchers found a similar protective role for the Y chromosome gene UTY.

The SurfaceChIP-seq method enables inputs down to 30 cells as well as the ability to analyze multiple histone modifications in parallel.

Cincinnati Children's Hospital Medical Center researchers found that disease risk loci overlap with transcription factor binding sites.

CU Denver and UC San Francisco teams are independently performing whole-genome sequencing to find genes involved in reduced efficacy of a common bronchodilator drug.

The transcription factor FOXM1 marked meningioma cases with poorer outcomes and enhanced cell proliferation, based on integrated exome, expression, and epigenetic profiles.

This Week in PNAS

In PNAS this week: genetic diversity of MERS in African camels, centromere evolution in Cryptococcus, and more.

Chromatin immunoprecipitation sequencing showed divergent H4K16ac histone acetylation patterns in brain samples from young, old, and AD-affected individuals.

A genomic analysis of ependymomas from 42 patients led to nearly 1,700 suspected super enhancers, highlighting potentially targetable genes.

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An Australian-led team has generated a draft genome assembly of the invasive cane toad in hopes it will help in population control, the Sydney Morning Herald reports.

The New York Times reports that the US Department of Defense has implemented about half the recommendations made to improve safe handling of dangerous agents.

In PLOS this week: approach for teasing out archaic introgression in human genomes, immune transcription features in HCV infection, and more.

Stat News reports that Maryland is promoting itself to the biotech industry with a mobile billboard.