ChIP

The companies will combine their respective technologies to develop epigenetic assays for cancer patient stratification and personalized treatment.

Such an atlas could enable investigators to understand how genetic variants impact disease risk, define drug toxicities, improve therapies, and advance regenerative medicine.

A team led by Buck Institute for Research on Aging scientists has reported that ApoE4 binds the promoter regions of Alzheimer's disease genes, including SirT1.

This Week in Nature

In Nature this week: mouse genome functional analysis, more sensitive chromatin immunoprecipitation, and more.

NEW YORK (GenomeWeb) — Researchers from the University of Washington have won $233,077 from the National Institute of General Medical Sciences to develop a novel chromatin immunoprecipitation platform, PIXUL-ChIP, that will integrate sample harvesting and chromatin shearing with immunoprecipitati

WaferGen Biosystems said this week that the Salk Institute for Biological Studies has established a nano-qPCR core laboratory that will feature a WaferGen SmartChip system for high-throughput, real-time PCR studies.

NEW YORK (GenomeWeb News) – A transcription factor called ELF5 may be a main determinant of breast cancer type, a team of Australian researchers reported in PLOS Biology last night.

NEW YORK (GenomeWeb News) – An international collaboration involving more than 400 researchers working to characterize gene regulatory networks in the human genome is publishing dozens of new studies this week.

By a GenomeWeb staff reporter
NEW YORK (GenomeWeb News) – Colon cancers carry a telltale set of epigenetic enhancer sites that appear to mediate gene expression shifts in the disease, according to a new online study in Science.

The method, dubbed single-tube linear DNA amplification, or LinDA, is expected to facilitate genome-wide profiling of transcription factors and chromatin analyses using DNA obtained from just a few hundred cells.

Pages

Germany's Project DEAL has come to an agreement with the publisher Wiley over journal access and open-access publishing, ScienceInsider reports.

A Canadian panel recommends public coverage of the gene therapy Kymriah if its cost comes down, the Globe and Mail reports.

Researchers uncover additional loci associated with lifespan, which the Telegraph says could be folded into a genetic test.

In Nucleic Acids Research this week: new accurate quantification by sequencing approach, CNV breakpoints in Plasmodium falciparum, and more.