chemical genomics

The Infectious Disease Research Institute will use the grant to use "chemical genomics" medium- and high-throughput screening approaches to identify candidate targets against tuberculosis.

The Vancouver Prostate Centre will use funding from Genome BC to conduct computational chemogenomic screening of compounds in a search for new prostate cancer treatments.

BioFocus will provide Genentech with integrated medicinal chemistry, in vitro biology, and ADME services.

The Screen Machine

Premium

Chris Austin has built a world-class chemical genomics facility to develop screening assays for a whole host of biological systems and research purposes. Now he's looking for scientists to make the most of it.

The agency's new strategic plan will turn to 'omics and molecular pathway analysis to understand and monitor environmental toxicity concerns.

Scientists should “be very aware” of the “limitations” of bioluminescent reporters, and contemplate running control assays before interpreting data from high-throughput screens, NCGC researchers said.

Researchers from the National Institutes of Health's Chemical Genomics Center warn that the firefly luciferase enzyme may show enhanced activity with some compounds — potentially leading to false positive results.

Using DNA to sketch crime victims might not be a great idea, the NYTimes says.

Science has its own problem with sexual harassment. What do we do with the research these abusers produce, Wired asks.

Senate Republicans led by Senator Rand Paul (R-KY) are trying to change how the government funds basic research, reports ScienceInsider.

In Science this week: combining genomics and ecology to better understand the effects of natural selection on evolution, and more.