chemical genomics

The Infectious Disease Research Institute will use the grant to use "chemical genomics" medium- and high-throughput screening approaches to identify candidate targets against tuberculosis.

The Vancouver Prostate Centre will use funding from Genome BC to conduct computational chemogenomic screening of compounds in a search for new prostate cancer treatments.

BioFocus will provide Genentech with integrated medicinal chemistry, in vitro biology, and ADME services.

The Screen Machine

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Chris Austin has built a world-class chemical genomics facility to develop screening assays for a whole host of biological systems and research purposes. Now he's looking for scientists to make the most of it.

The agency's new strategic plan will turn to 'omics and molecular pathway analysis to understand and monitor environmental toxicity concerns.

Scientists should “be very aware” of the “limitations” of bioluminescent reporters, and contemplate running control assays before interpreting data from high-throughput screens, NCGC researchers said.

Researchers from the National Institutes of Health's Chemical Genomics Center warn that the firefly luciferase enzyme may show enhanced activity with some compounds — potentially leading to false positive results.

Cancer researcher Alan Rabson has died at 92, the New York Times reports.

As the National Guideline Clearinghouse goes dark, the ECRI Institute says it will pick up the slack.

In Genome Research this week: sequencing method examines proteins parasite uses to evade immune system, L1 insertions in cancer, and more.

The Atlantic reports on private Facebook support groups for people who receive unexpected parentage results from direct-to-consumer genetic tests.