cell lines
Pancreatic Cancer Study Uncovers Prognostic Splicing Signature
Researchers used transcriptome data to ID a splicing signature and splicing factor linked to poor outcomes in the basal-like pancreatic ductal adenocarcinoma subtype.
Investigational Cancer Drug Deemed Highly Mutagenic in Cell Line Sequencing Study
Using whole-genome sequencing on drug-exposed cell lines, researchers saw high mutation rates in control cell lines intermittently treated with a compound called CX-5461.
UK Bat Study Finds Coronaviruses With Potential to Develop Into Human Pathogens
Researchers used RNA sequencing on UK bat fecal samples to unearth several coronaviruses, including a sarbecovirus capable of binding to the human ACE2 receptor.
Pediatric Cancer Cell Atlas Uncovers Clues About Cancer Drivers, Treatment Targets
Using multiomic profiling coupled with functional assays and drug screens, researchers characterized hundreds of cell lines representing 18 childhood tumor types.
SEngine Precision Medicine, Gustave Roussy to Offer Cancer Drug Sensitivity Testing in Europe
The partners aim to accelerate the implementation of precision oncology in the region, beginning with a clinical trial of colorectal and pancreatic cancer patients.