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cell line authentification

Secondcell Bio Hopes to Make Creation of Cell Lines as Easy as Building Legos
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The New York City-based startup is offering a 20-year-old technology to build new cell lines to the wider scientific community for the first time.

Find Genomics' Cell Line Tracking Tool Aims to Improve Research Reproducibility
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The developers say the Find Cell software tool allows researchers to improve their lab workflows and monitor cell lines for changes.

Induced Pluripotent Stem Cell Variability Tallied Across Genomes

Researchers profiled the genotypes and phenotypes for more than 700 induced pluripotent stem cell lines, uncovering between-individual sources of variation. 

Genetic Analysis Reveals Misidentified Glioma Cell Line

Short tandem repeat and expression data indicate that the U87MG cell line in the ATCC collection no longer represents the glioma from which it was established.

Genetic Variability in MCF-7 Cancer Cell Line Could Have Implications for Reproducibility
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Considering the widespread use of the cell line, these findings could have significant implications for the research community. 

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The Scan

Study Examines Insights Gained by Adjunct Trio RNA Sequencing in Complex Pediatric Disease Cases

Researchers in AJHG explore the diagnostic utility of adding parent-child RNA-seq to genome sequencing in dozens of families with complex, undiagnosed genetic disease.

Clinical Genomic Lab Survey Looks at Workforce Needs

Investigators use a survey approach in Genetics in Medicine Open to assess technologist applications, retention, and workforce gaps at molecular genetics and clinical cytogenetics labs in the US.

Study Considers Gene Regulatory Features Available by Sequence-Based Modeling

Investigators in Genome Biology set sequence-based models against observational and perturbation assay data, finding distal enhancer models lag behind promoter predictions.

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.