cell line authentification

Researchers profiled the genotypes and phenotypes for more than 700 induced pluripotent stem cell lines, uncovering between-individual sources of variation. 

Short tandem repeat and expression data indicate that the U87MG cell line in the ATCC collection no longer represents the glioma from which it was established.

Considering the widespread use of the cell line, these findings could have significant implications for the research community. 

The firm will provide DNA from at least 50 mouse cell lines for use in a PCR-based validation assay.

NEW YORK (GenomeWeb News) – Promega is suing Life Technologies saying it infringes patents held by Promega covering the analysis of small tandem repeat loci for genetic analysis.

NEW YORK (GenomeWeb News) – Life Technologies has filed a suit asking a federal court to find that the firm does not infringe a patent held by Promega and it has retained rights under a licensing agreement related to cell line authentication and identification.

Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.