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cell line authentification

HeLa Variety

The University of Zurich's Ruedi Aebersold and his colleagues analyzed a dozen HeLa cell lines to find differences in gene expression, protein levels, and more.

No, Not That Line

Retraction Watch speaks with a researcher who hopes to nudge others away from using problematic cell lines.

Researchers profiled the genotypes and phenotypes for more than 700 induced pluripotent stem cell lines, uncovering between-individual sources of variation. 

Short tandem repeat and expression data indicate that the U87MG cell line in the ATCC collection no longer represents the glioma from which it was established.

Considering the widespread use of the cell line, these findings could have significant implications for the research community. 

The firm will provide DNA from at least 50 mouse cell lines for use in a PCR-based validation assay.

NEW YORK (GenomeWeb News) – Promega is suing Life Technologies saying it infringes patents held by Promega covering the analysis of small tandem repeat loci for genetic analysis.

NEW YORK (GenomeWeb News) – Life Technologies has filed a suit asking a federal court to find that the firm does not infringe a patent held by Promega and it has retained rights under a licensing agreement related to cell line authentication and identification.

The Washington Post reports that Herbert Tabor, who worked at the US National Institutes of Health for 77 years, has died at 101.

The World Bank is seeking approval for a $12 billion plan to provide low-income nations with funds to procure SARS-CoV-2 vaccines, according to Reuters.

Science writes that public health officials and others are debating whether cycle threshold values should be included on SARS-CoV-2 results.

In Nucleic Acids Research this week: online database of SARS-CoV-2 protein structures, atlas of the human brain, and more.