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cell-based assays

The high-throughput and assay development agreement will focus on identifying and validating hits for an immune disease and cancer-related target.

ZenBio will offer the cell lines in cryopreserved and cultured forms, as well as contract services including assay development and compound screening.

The companies will develop miniaturized cell-based assays using high-throughput flow cytometry and computational models for hepatotoxicity testing.

Cisbio Bioassays will use CellAura's flourescent reagents for non-radioactive assays for cellular studies.

StemCells said the restructuring will support the growth of the stem cell culture and cell-based assay platforms it inherited as part of its estimated $4.8 million acquisition of SCS in April.

Promega's luciferase reporters will be used in SABiosciences' assays.

The University of Lodz will use the system in its gene expression and screening projects.

The firms established a multi-year alliance, under which scientists from the companies will work together to develop hESC-based products for drug discovery.

Appearing in the online editions of Fungal Genetics and Biology and Microbiology, the papers describe the use of Biolog's Phenotype Microarray platform to research secondary pathways in F. graminearum, which is responsible for head blight and crop losses.

The firms are collaborating on providing drug-discovery support services with a focus on predictive toxicology.


Nature News reports that recent proposed changes to the US National Science Foundation have raised concerns about a shift away from the agency's focus on basic research.

Noel Rose, the "father of autoimmunity," has died at 92, the Washington Post reports.

According to CNN, Legionella was discovered in buildings leased by the Centers for Disease Control and Prevention as they reopened following coronavirus pandemic-related closures.

In PLOS this week: genetic analysis of malaria parasite populations in Southeast Asia, genomic surveillance of yellow fever virus in São Paulo, and more.