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CE sequencing

Researchers from Johns Hopkins University and the BC Cancer Agency used exome sequencing and transcriptome sequencing, respectively, to find a novel, commonly mutated gene in ovarian clear-cell carcinoma.

Researchers reported yesterday that they have sequenced the draft genome of the Golden Delicious apple variety.

A University of California at Berkeley and Department of Energy Joint Genome Institute-led research team reported today that they have sequenced the genome of a sea sponge, Amphimedon queenslandica, and identified gene families in the genome that are shared with other multicellular animals.

The researchers identified an accumulation of rare variants in four genes identified by GWAS. They now plan to sequence more candidate genes using Sanger sequencing and, eventually, next-generation sequencing.

Researchers from the National Human Genome Research Institute and the University of Alaska at Fairbanks used microsatellite analyses to explore the genetics of Alaskan sled dogs specialized for sprint or distance racing.

By sequencing the genomes of the human body louse and an endosymbiotic bacterial species living inside it, researchers have started finding clues to louse biology and adaptation.

Last year, the consortium, which involves researchers, funding agencies, and industry representatives from Canada, Chile, and Norway, awarded a $6 million contract to Beckman Coulter Genomics for the first phase of the project, which uses Sanger sequencing.

 By genotyping nuclear and mitochondrial sequences from fruit-eating bats in the Caribbean and mainland South America, a Texas Tech University research team has found evidence for hybridization in a Caribbean species called Artibeus schwartzi.

The assay, which combines triplet repeat-primed PCR with high-throughput automated capillary electrophoresis, is fast enough and sensitive enough to serve as the basis for a first-tier routine population screen for fragile X and associated conditions, according to the researchers.

The new sequence data includes 156 new insertions corresponding to novel exons and noncoding regions. The researchers also compared their data to a next-generation sequence and de novo assembled genome, highlighting the advantages and limitations of the newer technology.

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Retraction Watch writes that a cancer researcher has had an eighth paper retracted.

Computational biologist James Taylor has died, according to Johns Hopkins University.

The Centers for Disease Control and Prevention is starting to test people for SARS-CoV-2 antibodies, according to the New York Times.

In PLOS this week: features of tumor-infiltrating immune cells, regulatory effects of SNPs associated with prostate cancer risk, and more.