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CE sequencing

Researchers from the Wellcome Trust Sanger Institute and elsewhere used deep sequencing to improve on existing estimates for mutation rates in the human genome.

A group of researchers from the Universities of Arizona and California have garnered genetic evidence suggesting modern human populations underwent an exponential expansion in Africa starting some 40,000 years ago.

The ICSASG recommends Sanger sequencing or a technology of equivalent read length and quality, rather than one of the current next-generation sequencing technologies, for the first phase of the project. The second phase will likely involve novel sequencing technologies.

Sequencing for Disease

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Clinical labs are testing the waters with next-gen sequencers. Utah's Rong Mao reports on early work with tests for cystic fibrosis and other diseases.

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Kelvin Droegemeier, the director of the White House Office of Science and Technology Policy, is the new acting director of the US National Science Foundation.

An opinion piece at the Guardian discusses the state of SARS-CoV-2 testing in the UK.

Wired reports the University of California, Berkeley's Innovative Genomics Institute has transformed itself into a diagnostic lab to run SARS-CoV-2 tests.

In Nature this week: direct-capture Perturb-seq approach for combinatorial single-cell CRISPR screens, potential uses of genome-editing in breeding crops, and more.