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CastPCR

The results, if confirmed further, could help pick out unresponsive patients early, opening up other therapeutic options for them.

Cynvenio Biosystems said this week that it expects to gain CLIA certification in the next few weeks for its circulating tumor cell technology.

By Ben Butkus
Life Technologies this week announced the expansion of its TaqMan Mutation Detection Assays based on competitive allele-specific TaqMan, or Cast, PCR technology.

The mutation detection assays for KRAS, BRAF, and EGFR genes are based on competitive allele-specific TaqMan PCR. The company claims the assays are sensitive enough to detect single mutant molecules in a background of 1 million normal copies.

Initial unpublished data from studies employing the method, competitive allele-specific TaqMan PCR, suggest that it can detect single rare mutant alleles in up to a million wild-type sequences with a high degree of specificity.

A New Zealand minister says the country's genetic modification laws need to be re-examined to help combat climate change, the New Zealand Herald reports.

A new analysis finds some cancers receive more nonprofit dollars than others.

An Australian mother's conviction in the deaths of her children may be re-examined after finding that two of the children carried a cardiac arrhythmia-linked gene variant.

In Science this week: comparative analysis of sex differences in mammal gene expression, and more.