CastPCR

The results, if confirmed further, could help pick out unresponsive patients early, opening up other therapeutic options for them.

Cynvenio Biosystems said this week that it expects to gain CLIA certification in the next few weeks for its circulating tumor cell technology.

By Ben Butkus
Life Technologies this week announced the expansion of its TaqMan Mutation Detection Assays based on competitive allele-specific TaqMan, or Cast, PCR technology.

The mutation detection assays for KRAS, BRAF, and EGFR genes are based on competitive allele-specific TaqMan PCR. The company claims the assays are sensitive enough to detect single mutant molecules in a background of 1 million normal copies.

Initial unpublished data from studies employing the method, competitive allele-specific TaqMan PCR, suggest that it can detect single rare mutant alleles in up to a million wild-type sequences with a high degree of specificity.

Though many details have yet to be worked out, the draft deal for the UK's withdrawal from the EU is giving researchers some hints for what they can expect, Nature News says.

DNA testing has solved a 100-year-old mystery contained in the skull and teeth samples of a now-extinct monkey that once inhabited Jamaica, Gizmodo reports.

As the UN ponders a ban on gene drives, one malaria researcher says there are less dramatic ways to fight the disease in Africa than unleashing GM mosquitoes on a whole continent.

In Nature this week: an improved reference genome of the Aedes aegypti mosquito, genomes of four species of truffles, and more.