CastPCR | GenomeWeb

CastPCR

The results, if confirmed further, could help pick out unresponsive patients early, opening up other therapeutic options for them.

Cynvenio Biosystems said this week that it expects to gain CLIA certification in the next few weeks for its circulating tumor cell technology.

By Ben Butkus
Life Technologies this week announced the expansion of its TaqMan Mutation Detection Assays based on competitive allele-specific TaqMan, or Cast, PCR technology.

The mutation detection assays for KRAS, BRAF, and EGFR genes are based on competitive allele-specific TaqMan PCR. The company claims the assays are sensitive enough to detect single mutant molecules in a background of 1 million normal copies.

Initial unpublished data from studies employing the method, competitive allele-specific TaqMan PCR, suggest that it can detect single rare mutant alleles in up to a million wild-type sequences with a high degree of specificity.

In Science this week: metagenomic-based technique for determining protein structure, and more.

An academic laments the rise of narcissism in the sciences, the Guardian reports.

Outgoing FDA commissioner Robert Califf writes in an editorial that the agency can help boost innovation.

The Trump transition team has asked NIH Director Francis Collins to remain at his post, though it's unclear for how long that will be.