capture-based sequencing

Researchers found relevant non-coding mutations in colorectal cancer cell lines by systematically profiling chromosome interactions at promoter fragments.

Using Hi-C, genome sequencing, and optical mapping, researchers profiled structural variants in multiple cancer cell lines, leading to potential non-coding drivers.

By sequencing a handful of individuals who lived in Morocco some 13,900 to 15,100 years ago, investigators found clues to past population mergers in North Africa.

At the AGBT conference this week, the DNA synthesis discussed the new capture products and its overall business.

Sophia Genetics has received a CE-IVD mark for a sequencing-based test that, combined with data analytics, is meant to improve detection of leukemia.

Using Neolithic and Chalcolithic period samples, researchers explored farming and hunter-gatherer admixture in populations from Hungary, Spain, and Germany.

Sarcophagus of Tadja, Abusir el-Meleq

The team uncovered ties to Near Eastern and Levant populations with mitochondrial genome sequences and genome-wide SNP profiles for up to 90 Egyptian mummies.

Investigators from Germany, the US, China, and elsewhere have identified an ancient Romanian man just a few generations removed from a Neanderthal ancestor.

Researchers from the University of Washington have published a proof-of-principle study on the use of genomic capture and high-throughput sequencing for finding mutations in breast and ovarian cancer risk genes.

Researchers are refining a tool to predict a woman's risk of developing breast cancer, according to the Guardian.

According to Stat News, the partial government shutdown in the US could soon affect the ability of the Food and Drug Administration to review new drugs.

In PNAS this week: gypsy moth genome sequenced, phylogenomic analysis of Polyneopterans, and more.

CNN reports that people's genes tend to have a greater influence on their risk of developing disease than their environment, but it varies by phenotype.