capture-based sequencing
Ancient Genomes from Bohemia Point to Complex Population Encounters in Central Europe
With 271 new or previously sequenced genomes from Bohemia, researchers followed population dynamics in the region between some 3,600 to 6,900 years ago.
Twist Bioscience, Biotia Nab FDA EUA for Hybridization-Based NGS SARS-CoV-2 Assay
The hybridization-based test may provide better detection of emerging COVID-19 variants of concern, due to a higher tolerance for probe mismatches than in PCR.
Ancient Viking Variola Virus Genomes Shed Light on Evolution of Modern Smallpox Virus
Researchers used sequence data from variola virus strains in 11 "Viking Age" individuals from northern Europe to gain new clues about smallpox evolution.
These hybrid capture-based methods target gene transcripts of interest, which could shrink sequencing costs for some experiments by as much as 90 percent.
Twist Bioscience Announces $100M Public Stock Offering
The offering of common stock will be the second for Twist this year and the third since the company made its initial public offering in October 2018.