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capture-based sequencing

Researchers used sequence data from variola virus strains in 11 "Viking Age" individuals from northern Europe to gain new clues about smallpox evolution.

These hybrid capture-based methods target gene transcripts of interest, which could shrink sequencing costs for some experiments by as much as 90 percent.

The offering of common stock will be the second for Twist this year and the third since the company made its initial public offering in October 2018.

The UK's Biosearch Technologies will distribute Arbor Biosciences' myBaits custom, targeted NGS panels to agricultural and seed breeding companies.

By sequencing 10 Bronze, early Iron, and late Iron Age individuals, researchers retraced ancestry patterns at a Philistine port city in present-day Israel.

Researchers identified blood lipid-associated adipose tissue methylation marks with an epigenome-wide association study on obese individuals undergoing bariatric surgery.

Researchers sequenced 45 individuals from the Caucasus and steppe region between 3,500 and 6,500 years ago, teasing out distinct populations and shared relationships.

Researchers found relevant non-coding mutations in colorectal cancer cell lines by systematically profiling chromosome interactions at promoter fragments.

Using Hi-C, genome sequencing, and optical mapping, researchers profiled structural variants in multiple cancer cell lines, leading to potential non-coding drivers.

By sequencing a handful of individuals who lived in Morocco some 13,900 to 15,100 years ago, investigators found clues to past population mergers in North Africa.

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The US Food and Drug Administration is to announce stricter standards for emergency authorizations of SARS-CoV-2 vaccines, reports the Washington Post.

Bloomberg reports the budget of Operation Warp Speed is actually $18 billion, higher than the number typically cited.

The Associated Press reports Johnson & Johnson is starting a late-stage clinical trial of its candidate SARS-CoV-2 vaccine.

In Genome Research this week: genomic analysis reveals role of super-spreaders in SARS-CoV-2, epigenetic drivers of cancer, and more.