cancer sequencing New Mutational Signatures Detected in Cancers Profiled for UK's 100K Genomes Project Researchers analyzed genome sequences from 18,640 tumors profiled for the 100kGP and other efforts, leading to dozens of substitution signatures and a new signature detection algorithm. Thermo Fisher Scientific Obtains CE Mark for Ion Torrent Genexus Dx Integrated Sequencer The company is developing a sample-to-report diagnostic workflow and a portfolio of clinically validated assays for the sequencing platform. Cancer Genome Analysis Points to Biallelic Mutations to Inform Variant Interpretation Investigators saw mutations affecting both maternal and paternal alleles in 21 percent of tumors in a pan-cancer collection, including mutations reflecting a tumor's mutagenic history. Large-Scale Cancer Genome Analysis Reveals Mutation Clusters That Can Inform Prognosis With genome sequences for thousands of tumors, researchers identified somatic mutation clusters, mechanisms behind them, and potential ties to patient outcomes. BostonGene Partners with NEC to Offer Tumor Portrait Tests Internationally NEC, an investor in BostonGene, will initially help provide Tumor Portrait to hospitals in Japan using its healthcare and life science network. May 7, 2021 NorthShore, Sema4 Partnership Aims to Demonstrate Utility of Genomics for Personalized Care Premium Apr 2, 2021 Illumina Parries FTC Challenge to Grail Acquisition With Deals for Competing Customers Premium Mar 16, 2021 Illumina, Geneseeq Technology to Collaborate on IVD Cancer Testing Kits in China Mar 3, 2021 Nonprofit Count Me In to Return Genomic Results to Patients With Rare Cancers Premium Feb 25, 2021 Natera Revenues Grow 35 Percent in Q4 Feb 25, 2021 NantHealth Q4 Revenues Flat From Year Ago Feb 17, 2021 Exact Sciences Sketches Out Strategy for End-to-End Cancer Testing With Ashion Acquisition Premium Feb 9, 2021 UK Startup Gabriel Precision Oncology Leans on Congenica to Broaden NGS Use in Cancer Testing Premium Feb 2, 2021 Congenica, Gabriel Precision Oncology Partner on Clinical Interpretation for Somatic Cancer Testing Jan 13, 2021 At JPM, Natera CEO Lays Out Growth Potential for NIPT, Transplant, Cancer Testing Jan 11, 2021 Illumina CEO Discusses Pan-Cancer IVD Assay, CDx Collaborations at JP Morgan Jan 6, 2021 TwinStrand Biosciences Explores Error Reduction Sequencing Tech in Various Applications Premium Dec 1, 2020 Illumina, PierianDx Expand Partnership on Cancer Panel Test Reporting Nov 24, 2020 Clinicians Face New Intervention Questions as Clonal Hematopoiesis Mutation Data Evolves Premium Nov 5, 2020 NantHealth Q3 Revenues Tick Up Slightly Oct 14, 2020 PierianDx, Pillar Biosciences Partner to Streamline NGS Cancer Analysis Sep 21, 2020 Grail Deal Will Enable Illumina to Expand From Tech Innovator to Diagnostics Provider Premium Sep 21, 2020 JP Morgan Downgrades Illumina to Neutral on Grail Deal Sep 16, 2020 Illumina's Stock Falls 9 Percent on Grail Acquisition Rumors Sep 16, 2020 LabCorp's Covance Joins Tempus TIME Trial Program Load More Breaking News Single-Nucleus Chromatin Accessibility Profiling in Coronary Artery Disease Points to Mechanisms ALL Genomes Marked by High DNA Methylation Levels Cepheid Gets CE Mark for Updated Rapid COVID MDx Test Mainz Biomed, Dante Labs Partner to Commercialize ColoAlert in Europe, UAE CellCarta Acquires Rights to Targeted Protein Assays from Fred Hutch Spinout Precision Assays Genetic Analysis, Omnigene Medical Technologies Ink Distribution, Tech Transfer Deal The Scan Monkeypox Case Found in US The New York Times says that a case of monkeypox has now been reported in the US. Effects on Fetal Screening Wired writes that changes to US abortion laws could affect screening for fatal congenital conditions. 'Pharma Bro' Out of Prison The Wall Street Journal reports that Martin Shkreli has been released from prison to a halfway house. Nature Papers Present Cultivate Oat Genome, Benchmarking of Spatial and Single-Cell Transcriptomic Integration Methods In Nature this week: reference genome of the cultivated oat, and more.