branched DNA

Less than a year after Affymetrix bought eBioscience, the array vendor is finding ways to combine its background in microarray and branched-DNA genotyping and expression with eBio's flow cytometry reagents and multiplex immunoassay portfolios.

The expansion of the QuantiGene product line, gained through the GeneChip maker's 2008 purchase of Panomics, is part of an overall company effort to diversify its business.

While Affy officials said they were "surprised" by the decrease in service revenues, they cited "steady progress" in the company's genotyping and expression businesses.

Affymetrix retains a majority share of the global array-based gene-expression market and believes its branched DNA-based QuantiGene kits, on board since its 2008 acquisition of Panomics, will spur future growth and provide it a platform to challenge RT-PCR.

Siemens filed the rehearing request in response to a February ruling that Enzo's patent application covering its nucleic acid signal amplification technology predates and invalidates a patent owned by Siemens and relating to its branched DNA diagnostic systems.

The Seattle Times writes that pharmacogenomics testing can help choose medications that may work best for people with depression.

Researchers report that deleting one gene from butterflies affects their wing coloration patterns, according to the Washington Post.

In PNAS this week: genome sequencing of weevil symbionts, retinoid X receptor deletion in lung cancer metastasis, and more.

Sequencing could help combat foodborne illnesses, according to a blog post by Food and Drug Administration officials.