branched DNA

Less than a year after Affymetrix bought eBioscience, the array vendor is finding ways to combine its background in microarray and branched-DNA genotyping and expression with eBio's flow cytometry reagents and multiplex immunoassay portfolios.

The expansion of the QuantiGene product line, gained through the GeneChip maker's 2008 purchase of Panomics, is part of an overall company effort to diversify its business.

While Affy officials said they were "surprised" by the decrease in service revenues, they cited "steady progress" in the company's genotyping and expression businesses.

Affymetrix retains a majority share of the global array-based gene-expression market and believes its branched DNA-based QuantiGene kits, on board since its 2008 acquisition of Panomics, will spur future growth and provide it a platform to challenge RT-PCR.

Siemens filed the rehearing request in response to a February ruling that Enzo's patent application covering its nucleic acid signal amplification technology predates and invalidates a patent owned by Siemens and relating to its branched DNA diagnostic systems.

The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.