bisulfite sequencing

The Epigenetics For Female Personalised Cancer Care (EpiFemCare) project recently published its findings in two papers in the journal Genome Medicine.

Investigators identified mutation, expression, and methylation differences in colorectal polyps from individuals with or without colorectal cancer.

The companies will integrate Cambridge's TrueMethyl technology for oxidative bisulfite sequencing with NuGen's sequencing library preparation kits.

Investigators identified changes in methylation at neurobiology-related genes when comparing blood methylation in twin pairs discordant for ALS.

This Week in Cell

In Cell this week: DNA methylation and T cell exhaustion, longevity in C. elegans, and more.

Results from up to eight stages of mouse or human retina development highlight the importance of histone modifications and other epigenetic shifts during differentiation.

In Genome Biology this week: methylation-based predictor of age in mice, population genetics of the common bean, and more.

This Week in PNAS

In PNAS this week: effects of activating KRAS mutations in lung adenocarcinoma, stranded bisulfite sequencing method, and more.

The University of California, Los Angeles-led team said the approach outperformed two established classification methods.

This Week in PNAS

In PNAS this week: transcriptional patterns in breast cancer cell lines, study of non-CG methylation, and more.


Berkeley researchers have engineered yeast to make the molecule behind the hoppy taste of beer, Quartz reports.

King's College London researchers examine the influence of school type and genetics on academic achievement.

FiveThirtyEight writes that most who take a direct-to-consumer BRCA1/2 genetic test won't learn much from it.

In Science this week: early life experience influence somatic variation in the genome, and more.