bisulfite sequencing
With bisulfite whole-genome sequencing of cfDNA from blood, researchers were able to monitor graft-versus-host disease, infection, graft failure, and disease relapse.
Thyroid Size, Function in Children Linked to Nutrition-Related DNA Methylation Mark
A trial in Gambia suggests PAX8 gene methylation in 2-year-olds corresponds to thyroid volume, hormone production, and physical features later in childhood.
Team Tracks Genetic Factors Linked to Severe COVID-19, Other Viral Infections in Children
At ACMG, researchers presented results from an ongoing effort using a growing sample collection to find genetic contributors to severe viral infections in children.
Pancreatic Cancer Subtype With Poor Outcomes Shows Low Methylation, High Interferon Signature
The aggressive subtype, uncovered by a team of researchers in Germany, may also be susceptible to targeted therapy that blocks interferon signaling.
Prostate Cancer Metastasis Linked to Development-Related Epigenetic Shift
Transcription factor reprogramming during prostate cancer metastases appears to involve epigenetic changes that resemble those at play during prostate development, new research finds.