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This Week in PNAS

In PNAS this week: transcriptional patterns in breast cancer cell lines, study of non-CG methylation, and more.

Researchers showed in a new study that patterns of methylation co-occuring at different sites could help distinguish cancer DNA in the blood, and mark its original source in body.

An epigenetic analysis showed that the tumors all shared a certain DNA methylation signature, but that methylation patterns varied between samples.

Researchers analyzed cytosine methylation profiles for 34 angiosperm plants, considering methylation levels and distribution across flowering plant families.

In Genome Research this week: targets of ALL gene fusion, genetic variation underlying Brachypodium DNA methylation, and more.

This Week in PNAS

In PNAS this week: Arabidopsis methylation patterns, models for estimating heritability, and more.

The researchers said that the methylation mark could potentially be used as a noninvasive biomarker for certain tumor types. 

In a paper published today in Nature Methods, the researchers applied scM&T-seq to profile the transcriptomes and epigenomes of mouse embryonic stem cells.

A team of Austrian researchers has developed a high-throughput pipeline to uncover and analyze DNA methylation without relying on a reference genome.

This Week in PNAS

In PNAS this week: variant protective against Alzheimer's disease, effect of whole-genome duplication on methylation in rice, and more.

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Startup companies are taking on personalized medicine, CNET reports.

Bruce Booth writes at Life Sci VC that biotech clusters like Boston and San Francisco are getting even more consolidated.

The Verge speaks with Mark and Scott Kelly, who are the subjects of NASA's Twin Study.

In Genome Biology this week: genes linked to Hirschsprung disease, structural variant patterns in autism, and more.