bisulfite sequencing
Team Tracks Genetic Factors Linked to Severe COVID-19, Other Viral Infections in Children
At ACMG, researchers presented results from an ongoing effort using a growing sample collection to find genetic contributors to severe viral infections in children.
Pancreatic Cancer Subtype With Poor Outcomes Shows Low Methylation, High Interferon Signature
The aggressive subtype, uncovered by a team of researchers in Germany, may also be susceptible to targeted therapy that blocks interferon signaling.
Prostate Cancer Metastasis Linked to Development-Related Epigenetic Shift
Transcription factor reprogramming during prostate cancer metastases appears to involve epigenetic changes that resemble those at play during prostate development, new research finds.
Metastatic Prostate Cancer Methylation Analysis Reveals Subtype, Ties to Driver Genes
While a subset of metastatic castration-resistant tumors was marked by enhanced methylation, the analysis also pointed to recurrently hypomethylated regions.
Translation of Dog Years Into Human Years Updated With Epigenetic Analysis
Dogs age more rapidly in their early years but then age more slowly later on, a DNA methylome analysis found, changing how dogs' ages are translated to human ages.