bisulfite sequencing Team Tracks Genetic Factors Linked to Severe COVID-19, Other Viral Infections in Children At ACMG, researchers presented results from an ongoing effort using a growing sample collection to find genetic contributors to severe viral infections in children. Pancreatic Cancer Subtype With Poor Outcomes Shows Low Methylation, High Interferon Signature The aggressive subtype, uncovered by a team of researchers in Germany, may also be susceptible to targeted therapy that blocks interferon signaling. Prostate Cancer Metastasis Linked to Development-Related Epigenetic Shift Transcription factor reprogramming during prostate cancer metastases appears to involve epigenetic changes that resemble those at play during prostate development, new research finds. Metastatic Prostate Cancer Methylation Analysis Reveals Subtype, Ties to Driver Genes While a subset of metastatic castration-resistant tumors was marked by enhanced methylation, the analysis also pointed to recurrently hypomethylated regions. Translation of Dog Years Into Human Years Updated With Epigenetic Analysis Dogs age more rapidly in their early years but then age more slowly later on, a DNA methylome analysis found, changing how dogs' ages are translated to human ages. Jun 11, 2020 Avida Biomed Developing Hybridization-Based Methylation Sequencing Panels for Cancer Dx Premium Jun 3, 2020 Base Genomics Raises $11M to Support Commercialization of Methylation Sequencing Platform Premium Apr 30, 2020 Washington University, BostonGene Expand Kidney Cancer Research Collaboration Mar 25, 2020 Prostate Cancer Cases in China Show Recurrent Alterations Distinct From Western Cohorts Sep 16, 2019 MRSA Susceptibility Study Uncovers Protective Variant in Methyltransferase May 15, 2019 Single-Cell Methylation Analysis Reveals CLL Evolution, Lineages With Distinct Treatment Responses Feb 26, 2019 University of Oxford Team to Commercialize Bisulfite-Free Methylation Sequencing Method Premium Feb 15, 2019 Obesity-Related Gene Methylation Changes Connected to BMI in Healthy Adolescents Feb 14, 2019 Ribosomal DNA Methylation May Serve as Clock of Aging in Mammals Dec 4, 2018 Grail Launches New Early Cancer Detection Study, Refocuses Strategy to Multi-Cancer Test Premium Aug 28, 2018 Epigenetics of Glioblastoma Progression Characterized with Integrated Data Aug 23, 2018 Multi-Omic Analysis of Rhabdomyosarcoma Points to Drug Targets in Deregulated Pathways Jun 14, 2018 Researchers Describe Improved Epigenetic Cancer Detection Method Premium Jun 5, 2018 Oncologists Digest Early Detection Data from Grail's CCGA Study at ASCO Premium Feb 28, 2018 European Study Yields New Cell-Free DNA Methylation Markers for Ovarian, Breast Cancers Premium Feb 16, 2018 Colorectal Cancer Clues Provided by Polyp Profiles Aug 15, 2017 Cambridge Epigenetix, NuGen Form Epigenetic Sequencing Partnership Aug 11, 2017 ALS Study Sees Blood Methylation Differences Between Twins Discordant for Disease May 4, 2017 Retina Development, Retinoblastoma Regulation Revealed in Pediatric Cancer Genome Project Paper Mar 24, 2017 CancerLocator Tool Aims to Non-Invasively Diagnose Cancer, Pinpoint Tissue of Origin Load More Breaking News Quest Diagnostics to Offer Biocept's Target Selector NGS Lung Cancer Test Novacyt 2020 Revenues Surge on Strong Demand for SARS-CoV-2 Testing Products Leidos Wins CDC Bioinformatics Contract Worth up to $13M Thermo Fisher Scientific Next-Generation SARS-CoV-2 PCR Test Nabs CE-IVD Mark Cytosine Base Editor Enables Genome-Wide Genetic Function Screening G42 Healthcare, Seegene to Offer Mobile Molecular Diagnostic Labs in Middle East, North Africa The Scan Renewed Gain-of-Function Worries The New York Times writes that the pandemic is renewing concerns about gain-of-function research. Who's Getting the Patents? A trio of researchers has analyzed gender trends in biomedical patents issued between 1976 and 2010 in the US, New Scientist reports. Other Uses CBS Sunday Morning looks at how mRNA vaccine technology could be applied beyond SARS-CoV-2. PLOS Papers Present Analysis of Cervicovaginal Microbiome, Glycosylation in Model Archaea, More In PLOS this week: functional potential of the cervicovaginal microbiome, glycosylation patterns in model archaea, and more.