biomarker detection
New Epigenomic Biomarker Could Predict CAR T-Cell Therapy Resistance in Advanced Childhood Leukemia
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At AACR, researchers described how pediatric ALL patients who don't respond to anti-CD19 CAR T-cell therapy have cancers with a unique, stem cell-like epigenome.
Zentalis Pharmaceuticals, Caris Life Sciences Ink Precision Oncology Partnership
Caris will use its platform to sequence solid tumor patients' full exomes and transcriptomes to determine eligibility for Zentalis' Wee1 inhibitor ZN-c3.
The 32-gene signature showed potential in predicting South Korean gastric cancer patients' overall survival and response to chemotherapy and immunotherapy.
ESMO Oncologists Debate Optimal Timing for Broad NGS, Align on Key Barriers to Precision Oncology
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Oncologists argued for and against comprehensive NGS at the point of diagnosis but agreed on the need to address quality and cost barriers first.
Immunovia, JW BioScience Ink Licensing Agreement for Early Pancreatic Cancer Detection Biomarkers
Immunovia said that it has secured intellectual property rights to the biomarkers, which are part of the diagnostic signature for its Immray PanCan-d blood test.