aptamers | GenomeWeb

aptamers

With the precision of PCR, the method could ultimately be used to build faster, simpler diagnostics.

SomaLogic Raises $10M

NEW YORK (GenomeWeb News) – SomaLogic has raised $10 million in equity financing, the company said in a document filed with the US Securities and Exchange Commission on Tuesday.

A team led by the Scripps Research Institute's Gerald Joyce is beginning its second year of an effort to develop a process analogous to quantitative PCR, in which the growth rate of a synthetic RNA molecule can be used as a quantitative measure of the initial concentration of a t

Proteomics diagnostics firm Somalogic reported data this week supporting the utility of its blood-based 13-protein panel for the detection of malignant mesothelioma.

By Adam Bonislawski
Somalogic last week published in PLoS One a study offering the first data on use of its aptamer-based Somascan platform in tissue samples.

The companies will partner on two clinical studies in dementia that combines Wavi's electroencephalogram-based biomarkers and SomaLogic's blood-based protein biomarkers.

Anticipating that NGS will become a key clinical tool in coming years, several proteomics firms and researchers are investigating it as a platform for protein biomarker detection assays that use nucleotides as capture agents, hoping to take advantage of the technology's precision and multiplexing ability.

The trials will evaluate biomarker panels for lung, colon, and prostate cancer, and may include a comparison of proteomics-based lung cancer tests from Somalogic and Celera.

In a study involving 38 mesothelioma patients and 62 asbestos-exposed controls, the 13-protein panel distinguished between the two with a sensitivity and specificity of 92 percent, said one of the researchers.

The agreement with NEC, which has purchased an equity stake in the company, is part of its plan to expand beyond its traditional focus on biomarker discovery and diagnostics development to become a "health information company" that can "provide actionable medical information to patients, physicians, and researchers," said an official.

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An opinion piece in the New York Times urges lawmakers to keep genetic protections in place.

Research funding in Canada is to remain mostly the same, ScienceInsider reports.

In Science this week: random DNA replication errors play role in cancer, and more.

The Bill and Melinda Gates Foundation embarks on an open-access publishing path.