antisense

NEW YORK (GenomeWeb) — Isis Pharmaceuticals and Santaris Pharma are currently negotiating a settlement to their roughly three-year-old patent-infringement lawsuit and believe there is "strong potential to settle" the litigation instead of going to trial, according to court documents filed this mo

NEW YORK (GenomeWeb) – While its primary focus remains on a class of novel cell membrane-disrupting antimicrobials, privately held Lakewood-Amedex is ramping up work on proprietary, orally delivered antisense molecules, with an eye to tackling influenza and, eventually, other viral diseases.

NEW YORK (GenomeWeb) – Marina Biotech this week took another step toward reestablishing itself as a player in the nucleic acids drug sector, regaining compliance with US Securities and Exchange Commission financial reporting requirements with the submission of the requisite information for 2012,

NEW YORK (GenomeWeb) – The National Institutes of Health this month announced two related funding opportunities for small businesses developing platform delivery technologies for nucleic acid therapeutics.

RNA drug developer Sarepta Therapeutics disclosed that its CSO, Art Krieg, has been terminated from his position at the company.
Details about the termination were not made public.

NEW YORK (GenomeWeb) – Researchers from Isis Pharmaceuticals this week published new data demonstrating the ability of a novel GalNAc conjugate to boost the potency of antisense oligonucleotides (ASOs) — including two it currently has in human trials — by as much as 10 fold in mice.

A US District Court last week denied Santaris Pharma's second bid to have a patent-infringement lawsuit filed against it by Isis Pharmaceuticals thrown out, ruling that the company again failed to establish that its allegedly infringing activities were protected by a US statute t

Isis Pharmaceuticals this month took issue with Santaris Pharma's latest attempt to use a safe harbor provision in US law to fend off patent infringement charges in the companies' ongoing legal war, arguing in a court filing that the legal protection only covers the development o

Santaris Pharma last week made another push to end the legal attack against it by Isis Pharmaceuticals, asking for the court that is hearing the companies' intellectual property lawsuit to rule that there was no infringement of the patents at the heart of the case.