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Jun 15, 2018

PDL1 Amplifications Mark Subset of Solid Tumors, May Point to Checkpoint Blockade Response

With sequence data for more than 118,000 tumors profiled at Foundation Medicine, investigators tracked PDL1 amplification prevalence and possible treatment implications.

May 16, 2018

Dutch Researchers Develop Multiplex RT-PCR Assay to Detect Bloodstream Infections

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The blood-based test could eventually become a rapid point-of-care diagnostic in the ICU, with startup Microbiome as a commercial vehicle.

Apr 14, 2017

This Week in Science

In Science this week: CRISPR-based approach to diagnose disease, new whole-genome amplification approach, and more.

Sep 28, 2016

Toyota Designs New Genotyping by Sequencing Technology Platform for Crop Research

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The firm's technology, called genotyping by random amplicon sequencing, or GRAS, should improve the efficiency of identifying and selecting markers for crop improvement.

Jul 14, 2016

Sequence Bio Raises $1.6M in Equity

Including the current financing round, the company has raised a total of nearly $2.4 million. 

Mar 22, 2016

Researchers Sequence Chimpanzee Parasites to Learn About Evolution of Human Malaria Species

The research team used selective amplification to sequence whole genomes of the parasites, revealing new information about how they evolved to infect human hosts. 

Aug 27, 2015

Researchers Develop LR-PCR, NGS Combination Method to Detect PMS2 Gene Mutations

The scientists believe they have created a more accurate way to detect mutations that often lead to hereditary colorectal cancer.

Mar 18, 2015

Sygnis Inks Belgian Distribution Agreement with Sopachem for TruePrime

The partnership is the latest in a string of international distribution announcements for Sygnis' primer-free whole genome amplification technology.

Jan 08, 2015

Karolinska Team Demonstrates PCR-free NGS Method for Noninvasive Prenatal Diagnosis

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The researchers also showed that the method provides greater and more even coverage and less bias in GC rich regions compared to PCR-based sequencing.

Jul 28, 2014

FDA Clears Quidel's Amplivue Group A Strep Test

NEW YORK (GenomeWeb) — The US Food and Drug Administration has cleared for marketing Quidel's AmpliVue GAS Assay for detection of Group A Streptococcus from throat swabs in patients with symptoms of pharyngitis, the company announced today.

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The Scan

Not a Unique Challenge Anymore

The US National Institutes of Health and the Food and Drug Administration have proposed changing gene therapy oversight, the Associated Press reports.

Case Goes On

Nature News reports that the Salk Institute has asked for the scope of a gender discrimination lawsuit brought against it to be narrowed.

The Very Old, Very Young, and Very Talented

CNBC reports that the sequencing startup Veritas aims to sequence individuals who fall at extremes.

This Week in PLOS

In PLOS this week: genotyping of indigenous North African goats, program to simulate evolve and resequencing studies, and more.

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