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By employing distributed computational resources and a novel algorithm, the VariantSpark technology is able to process a trillion data points in 15 hours. 

The sequence-based analysis suggests oncogene-containing circular, extrachromosomal sequences occur in most cancer types and may correspond with poorer patient outcomes.

In Science this week: machine learning model predicts whether ion channel mutations will cause disease, and more.

With a new analytical tool, researchers uncovered ancient archaic hominin sequences in the Denisovan genome, along with human introgression into Neanderthals up to 300,000 years ago.

The company will provide proprietary algorithms for analyzing omics and imaging data to define predictors of drug response and identify new biomarkers.

In PLOS this week: identification of fungal species in subcutaneous infections, sequencing of Campylobacter found in raw meat from retail stores, and more.

M2Gen has seen its research database grow substantially, but now the firm must make the data useful across its clinical, pharma, and MDx partners.

In Nucleic Acids Research this week: algorithm to determine molecular sequence types and other microbial features, computational method to uncover R-loop structures, and more.

The SICILIAN algorithm, which uses statistical modeling to score candidate fusions in single-cell RNA sequencing data, is being used to map splice sites in individual tumor cells.

The Cold Spring Harbor Laboratory spinout will build predictive models for lung cancer progression and risk using its SpliceCore software platform.

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Novavax has begun a phase III trial of its SARS-CoV-2 vaccine, according to the New York Times.

Vox reports that the Trump Administration may limit student visas for individuals from some countries to two years.

The governor of New York says the state will conduct its own review of any SARS-CoV-2 vaccine, NPR reports.

This week in Science: Neanderthal Y chromosomes replaced by Homo sapiens Y chromosomes, and more.