Sponsors
A reference measurement procedure incorporating digital PCR can potentially be used with rare and emerging pathogens to help labs compare qPCR results, researchers said.
The retrospective results suggest that the test's sensitivity boost over other platforms can overcome the challenge of detecting ctDNA in adenocarcinomas.
BRCA2 Variants Classified in Saturation Genome Editing Studies
Research teams relied on CRISPR-Cas9-based editing and sequencing to perform high-throughput function evaluations of loss-of-function variants in exons 15 to 26 of BRCA2.
VA Launches Prostate Cancer Screening Study to Improve Early Detection, Personalize Recommendations
Premium
The study is evaluating the utility of a prostate cancer risk prediction model based on a polygenic score, family history, and a blended genome-exome sequencing approach.
Lessons from the Phase III ZEST trial could inform ongoing and future trials as they seek to use ctDNA to prove efficacy of novel adjuvant treatments.