Single-cell Epigenetic Errors Can Be Uncovered and Rescued, Study Shows | GenomeWeb

NEW YORK (GenomeWeb News) – Using a new single-cell DNA methylation analysis technique, researchers were able to detect DNA methylation errors in mice, they reported in Science today. Errors in methylation and other epigenetic changes have been linked to a number of human syndromes, the researchers added.

In this study, once the researchers probed a number of early stage mouse embryos at different loci and found such methylation errors, they endeavored to correct them through pronuclear transfer.

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