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In Silico: June 2002

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Bigger and Better

Creature by creature, the natural world is steadily yielding its secrets to the genome sequencers. But the sequencers are getting restless. Eager to push the envelope, microbiologists at The Institute for Genomic Research and at Craig Venter’s new Institute for Biological Energy Alternatives have an ambitious new goal: to decode the microbial world an ecosystem at a time.

Find “For TIGR and Venter, the Goal Now Is to Sequence Entire Ecosystems at a Time” by searching: ecosystems

Publish or Perish

NHGRI will commemorate the final draft of the human-genome sequence, slated to wrap up in April, with a series of 24 articles describing each chromosome. These articles, to be published through the end of next year, will be capped soon after by one final analysis paper.

Find “NHGRI: A Final Human-Genome Paper Will Appear” by searching: NHGRI

Raining Money

There’s good budget news from the Senate Appropriations Committee for two federal agencies that underwrite research and development in genomics. The committee approved a $5.3 billion budget for the National Science Foundation, an 11 percent increase over the fiscal year 2002 budget and $288 million more than the administration’s request.

Find “Budget Hikes Look Likely as Senate Committee Approves NSF and NIH Funding Bills” by searching: hikes WEEKLY

Survey Says

Researchers who have already acquired a TOF/TOF share their initial feedback on the instrument. By far the most notable observation concerning the TOF/TOFs — be they Bruker Daltonics or Applied Biosystems — was that researchers have yet to take advantage of the highly vaunted improvements in throughput that the instrument was meant to bring.

Find “MALDI-TOF/TOF Survey: Instruments Exceed Expectations, Early Users Say” by searching: survey WEEKLY

Orient Express

US and European bioinformatics sales may be in the doldrums, but software vendors that have established sales channels in Japan say that they are seeing relative — if not considerable — success. However, gaining a strong foothold in Japan is far more challenging than selling into the US and European markets.

Find “Bioinformatics Vendors Jump into a Japanese Market Primed for Growth” by searching: Japan WEEKLY

Microarray M&A

“We believe the market has moved from leading by innovation to leading by distribution…Distribution has become key.”

— Genomic Solutions CEO Jeffrey Williams, discussing why his company was acquired by lab supply company Harvard BioSciences

Find “GNSL Gobbled Up by Harvard Bio, Eppendorf Acquires Belgian Startup” by searching: gobbled

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.