For next-generation sequencing, paired reads — two stretches of sequenced DNA with an unsequenced insert of known size in between them — seem to be indispensable.
 
While paired reads have been crucial in Sanger sequencing for applications like de novo assemblies, “for short reads they are even more important as they add significant specificity,” said Chad Nusbaum, co-director of the genome sequencing and analysis program at the Broad Institute, in an e-mail message to In Sequence.
 

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American scientists find themselves once again warning the Trump administration not to dismiss science, the New Yorker report.

A new study suggests CRISPR could be used to save coral reefs from dying off, Forbes reports.

Researchers have found that the i-motif shape of DNA previously observed in the lab also exists in human cells, and that it may serve a purpose.

In PNAS this week: a genomic, transcriptomic, and metabolomic analysis of the tea plant, Arabidopsis thaliana's adaptations to specific local environments, and more.

Jun
12
Sponsored by
Philips Genomics

This webinar will highlight a comprehensive end-to-end solution for precision care in oncology, comprising sample acquisition through to sequencing and analysis, treatment recommendations, and follow-through.

Jun
28
Sponsored by
PerkinElmer

This webinar will review a standardized, high-throughput, and fully automated library prep protocol for human metagenomic analysis.