Aiming to provide more personalized treatment options for patients with monogenic diabetes, the University of Chicago Genetics Services Laboratory has launched a next-gen-sequencing-based gene panel to diagnose the disease.

Monogenic diabetes represents an estimated 1 to 2 percent of all diabetes mellitus cases. To date, more than 30 genes, which are highly expressed in pancreatic beta cells, have been implicated in the disease, a list that keeps growing.

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In PNAS this week: co-evolutionary signatures of insect hosts and bacterial symbionts, distinct transcript isoforms of high-grade ovarian cancer, and more.

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