A consortium of researchers in the UK plans to sequence the whole genomes of 50 patients with osteosarcoma, and the whole-exomes of 100 additional samples, in an effort to develop personalized blood tests for patients and identify novel genes involved in the disease.

The research is being funded by the Skeletal Cancer Action Trust, and involves researchers and clinicians from the University College London Cancer Institute, the Royal National Orthopaedic Hospital, and the Wellcome Trust Sanger Institute.

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In Nature this week: Icelandic genome sequences, approach to increase CRISPR efficiency, and more.

Testing showing "genetic incompatibilities" have led thousands of couples in Saudi Arabia to call off their weddings, the BBC reports.

Decode Genetics' ability to tell Icelanders, even ones the company hasn't sequenced, about their disease risk brings up ethical questions.

Genetic analysis of Britain's King Richard III and modern descendants of his relatives indicate breaks in the male line.

Apr
15
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This live online seminar will highlight recent trends in applying next-generation sequencing in the clinical setting, with a particular focus on oncology and rare disease.