Two Teams Devise New Methods for Sequencing-Based Methylation Profiling | GenomeWeb

Two teams of researchers have developed new methods that use high-throughput sequencing to profile DNA methylation that could be useful for analyzing methylation sites across large genomes.

One group, led by scientists at the University of California, San Diego, and Virginia Commonwealth University, devised a targeted methylation-profiling method that uses padlock probes to capture tens of thousands of bisulfite-converted short genomic targets containing CpG sites for sequencing.

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