Users of second-generation sequencing platforms from Illumina, 454/Roche, and Life Technologies/Applied Biosystems witnessed improvements in yield, read length, and data quality in 2008, though many struggled with technical problems relating to their instrument or reagents, according to a survey conducted by In Sequence at the end of 2008.

Also, the $10,000 human genome remained elusive in 2008, as the total cost for users to generate a gigabase of high-quality data ranged between $1,600 and $146,500 at the end of the year, depending on the platform.

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.