Technology No Longer a Hurdle, but Clinical NGS Faces Reimbursement and Biological Knowledge Issues | GenomeWeb

Next-generation sequencing is ready for the clinic, according to experts speaking on a panel at Hanson Wade's NGS Data Analysis conference in San Francisco last week.

Indeed, the technology is already being used in the clinic for certain applications. Sequencing-based noninvasive prenatal tests for aneuploidies have taken off; exome sequencing is being used in limited cases to diagnose rare diseases; and gene panels are being used in oncology.

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In PNAS this week: chromosome instability in S. cerevisiae, structural differences and sequence divergence in rice, and more.

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