NEW YORK (GenomeWeb News) – Colorectal cancer samples have fewer new mutations affecting mitochondrial DNA than do matched normal colon tissues, according to a study appearing online last night in PLoS Genetics.

Researchers from the US and Ireland tested matched tumor-normal samples from 20 individuals with colorectal carcinoma. Along with mitochondrial genome sequencing to look for clonally expanded mutations in the samples, they also relied on a random mutation assay to compare the frequency of non-clonal, random mutations in the mtDNA.

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In Nature this week: association between genome-wide homozygosity and traits like height and cognitive ability, improved CRISPR-Cas9 editing, and more.

A survey examines how age, political leanings, and more influence how Americans view certain scientific topics, the Associated Press reports.

A researcher who pleaded guilty to making false statements in research reports has been sentenced to four and a half years in prison and must pay $7.2 million back to the NIH.

The BabySeq project to study the risks and benefits of sequencing newborns is underway.

Jul
14
Sponsored by
Agilent Technologies

This online seminar will outline a recent example of the use of molecular barcoding in combination with next-generation sequencing to detect somatic mosaicism in cancer patients.