Team Sees Random Mutation Rate Dip in Colon Cancer Mitochondrial DNA | GenomeWeb

NEW YORK (GenomeWeb News) – Colorectal cancer samples have fewer new mutations affecting mitochondrial DNA than do matched normal colon tissues, according to a study appearing online last night in PLoS Genetics.

Researchers from the US and Ireland tested matched tumor-normal samples from 20 individuals with colorectal carcinoma. Along with mitochondrial genome sequencing to look for clonally expanded mutations in the samples, they also relied on a random mutation assay to compare the frequency of non-clonal, random mutations in the mtDNA.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.