By Julia Karow

In a proof-of-principle study, researchers at St. Jude Children's Research Hospital in Memphis, Tenn., have shown that even limited DNA sequencing can uncover important mutations that drive relapse in acute lymphoblastic leukemia patients and provide clues for more effective treatments. More comprehensive genome sequencing, they say, might deliver additional clinically relevant results.

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National Institutes of Health Director Francis Collins appears before a House subcommittee to discuss his agency's budget request.

In PNAS this week: Akt3 amplification in glioma progression, Tibetan Plateau frog genome, and more.

The US Supreme Court has declined to review a decision involving the use of "inadvertently shed" DNA in a police investigation and subsequent conviction.

A panel at the New York Times discusses anonymity and privacy of users of 23andMe's services when access to its database is offered for research.