Researchers in the UK have developed a targeted sequencing approach to detect mutations in circulating tumor DNA that they believe could eventually be developed as a clinical assay for early cancer diagnosis or to monitor disease progression and treatment response.

Their strategy, tagged-amplicon deep sequencing, or TAm-Seq, is a two-step amplification process that combines the Fluidigm Access Array with Illumina sequencing.

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In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.

Hong Kong is using DNA phenotyping to shame litterers.

A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.

NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.