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Synamatix, Thermo Fisher Scientific, Epicentre Biotechnologies

Synamatix has launched two software products designed for analyzing data from next-generation sequencing instruments. The first, SXOligosearch, is designed to map short sequences such as reads from the Illumina Genome Analyzer or oligonucleotide microarray probes. The second is an updated version of the company’s SynaSearch sequence searching software that has been “modified to process and map reads from the GS20 and FLX platforms from 454,” the company said.

Thermo Fisher Scientific has released a new range of Verso cDNA synthesis kits and RT-PCR kits. The company said that the kits combine a new reverse transcription enzyme with improved priming options and optimized buffers to generate a high yield of full-length cDNA. The new enzyme, called Verso RT, has an improved dynamic range that maximizes sensitivity “and allows users to detect a wider range of starting template concentrations,” the company said.

Epicentre Biotechnologies has released MasterAmp Tfl DNA Polymerase, a recombinant DNA polymerase with thermostability to approximately 95 degrees Celcius. The kit includes betaine as part of the MasterAmp 10X PCR Enhancer, which improves the yield and specificity of amplification of many target sequences, especially those containing a high G+C content or secondary structure, Epicentre said. The company said that it also improves the yield consistency of PCR products in multiplex PCR reactions.
Epicentre also released ScriptGuard RNase Inhibitor, which is designed to protect RNA samples “even when trace amounts of RNase are present,” the company said. ScriptGuard RNase Inhibitor does not interfere with enzymes commonly used to prepare RNA and is “substantially” more resistant to inactivation by oxidation than other RNase inhibitors, Epicentre said.

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.