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Synamatix, Sigma-Aldrich, National Center for Biotechnology Information

Synamatix has released SXOligoSearch, a new software application for mapping and analyzing reads from the Illumina Genome Analyzer. The company said that SXOligoSearch offers 80 percent higher coverage, 104-fold faster mapping, and 14 percent higher sensitivity compared to Illumina’s ELAND mapping software
A free demo of SXOligoSearch is available here.

Sigma-Aldrich has released the GenomePlex Tissue Whole Genome Amplification Kit, which includes all of the reagents needed for extraction and whole genome amplification from as little as 0.1 mg of fresh, frozen, or formalin-fixed paraffin-embedded tissue, the company said. Amplification results in microgram quantities of DNA.
The kit includes an improved tissue lysis and extraction procedure, which eliminates the need for deparaffinization or DNA purification, Sigma said. The product can be used in qPCR, microsatellite analysis, SNP analysis, comparative genomic hybridization, microarrays, and other genotyping analysis.

The National Center for Biotechnology Information has released GenBank 160.0 here. The release contains 77,248,690,945 base pairs and 73,078,143 entries. Uncompressed, the 160.0 flat files require about 280 GB for the sequence files only. The ASN.1 version requires around 237 GB.

The Scan

Driving Malaria-Carrying Mosquitoes Down

Researchers from the UK and Italy have tested a gene drive for mosquitoes to limit the spread of malaria, NPR reports.

Office Space to Lab Space

The New York Times writes that some empty office spaces are transforming into lab spaces.

Prion Pause to Investigate

Science reports that a moratorium on prion research has been imposed at French public research institutions.

Genome Research Papers on Gut Microbe Antibiotic Response, Single-Cell RNA-Seq Clues to Metabolism, More

In Genome Research this week: gut microbial response to antibiotic treatment, approach to gauge metabolic features from single-cell RNA sequencing, and more.