While whole-genome sequencing has proven useful for studying disease, it is less likely to be useful in predicting whether a healthy individual will develop a disease, a study recently published in Science Translational Medicine suggests. At the annual meeting of the American Association for Cancer Research in Chicago last month, Johns Hopkins Kimmel Cancer Center's Bert Vogelstein described the study done by his team. "Many believe, I among them, that we stand on the verge of a revolution," Vogelstein said at an AACR press conference.

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Senator Elizabeth Warren (D-Mass.) has released the results of a genetic ancestry analysis, the Boston Globe reports.

Retraction Watch's Ivan Oransky and Adam Marcus report that Harvard Medical School and Brigham and Women's Hospital have recommended that more than 30 papers from a former researcher be retracted.

Thomas Steitz, who won the 2009 chemistry Nobel Prize for his ribosome work, has died, the Washington Post reports.

In PLOS this week: mechanisms for genes implicated in coronary artery disease, rumen microbes and host genetics influence cow methane production, and more.