Study Points to New 'Pioneer Factor' Role in ER+ Breast Cancer Proliferation | GenomeWeb

By Andrea Anderson

NEW YORK (GenomeWeb News) – By profiling genomic patterns of a DNA-binding protein called PBX1 in breast cancer cells, Dartmouth Medical School researchers have shown that it serves as a "pioneer factor," paving the way for the estrogen receptor-positive breast cancer proliferation in response to the estrogen hormone.

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