NEW YORK (GenomeWeb News) – A new Science Translational Medicine study suggests high-throughput sequencing is effective for finding post-treatment leukemia cells that can lead to patient relapse.

Researchers from Fred Hutchinson Cancer Research Center, the University of Washington, and elsewhere used high-throughput sequencing to test matched pre- and post-chemotherapy samples from 43 individuals with T-lineage acute lymphoblastic leukemia, looking at how well their high-throughput sequencing method detected lingering leukemia cells compared with flow cytometry.

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In PNAS this week: spatiotemporal study of lncRNA expression, role of extrachromosomal, circular DNAs in yeast, and more.

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