Study Finds 454, Illumina Offer Similar Performance for Transcriptome Sequencing-Based SNP Discovery | GenomeWeb

By Andrea Anderson

In a head-to-head comparison of the Roche 454 GS FLX and Illumina GAII sequencing platforms, fish population researchers found that the two systems were equally capable of finding SNPs by sequencing the transcriptomes of fish from a species lacking a reference genome, though versions of the Illumina system introduced since the study was conducted appear to have a cost advantage over newer 454 instruments.

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