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SOLiD Whole Transcriptome Expression Kit

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Applied Biosystems said that it plans to launch a SOLiD Whole Transcriptome Expression kit as part of an early-access program in November. The new kit, which is based on Ambion technology, allows for up to 10 RNA libraries to be sequenced simultaneously. The technology conserves strandedness of cDNA. Using the kit, researchers first isolate and purify total RNA or mRNA from cell or tissue samples. Ribosomal RNA is then removed from these samples, followed by a RNA fragmentation step. Researchers then ligate adapters the RNA and convert it into cDNA, which is sequenced on the SOLiD system. ABI said it will also make data analysis tools available.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.