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SOLiD Small RNA Expression Kit, Lasergene v8.0

Applied Biosystems has released a SOLiD small RNA expression kit, a barcoding kit for multiplexing small RNA expression analysis on the SOLiD system. The technology, which is currently available to a limited number of customers through an early-access program, enables researchers to analyze up to 256 samples per run.

DNAStar has released Lasergene v8.0, a new version of its sequence analysis software. The new version has an improved primer design capability and new SNP discovery and reporting features that allow users to analyze and manage SNPs obtained from Sanger, 454, and Illumina sequencing platforms. Other new features simplify secondary protein structural analysis, expand primer walking capabilities, and simplify exports to the GenVision data visualization software. The software is compatible with DNAStar’s new next-generation sequence assembly tool, SeqMan NGen. Lasergene v8.0 works with Windows XP and Windows Vista, as well as Mac OS 10.4 and 10.5.

The Scan

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.

Study Reviews Family, Provider Responses to Rapid Whole-Genome Sequencing Follow-up

Investigators identified in the European Journal of Human Genetics variable follow-up practices after rapid whole-genome sequencing.

BMI-Related Variants Show Age-Related Stability in UK Biobank Participants

Researchers followed body mass index variant stability with genomic structural equation modeling and genome-wide association studies of 40- to 72-year olds in PLOS Genetics.

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.