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Home » Sponsors » Advances in Spatial Genomics » Single-Cell Transcriptome Study Links Gut Development, Pediatric Crohn's Disease

Single-Cell Transcriptome Study Links Gut Development, Pediatric Crohn's Disease

Dec 08, 2020
|
staff reporter

NEW YORK – Pediatric Crohn's disease appears to involve altered connections between intestinal cells and the reactivation of regulatory features found in developing gut cells, according to findings from a single-cell RNA sequencing study that analyzed human intestine samples, fetal intestinal organoids, and samples from children with or without the inflammatory bowel disease (IBD). 

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