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NEW YORK – In a single-cell analysis of myeloid malignancies, a team led by researchers at Memorial Sloan Kettering Cancer Center has found that acute myeloid leukemia (AML) is dominated by a small number of clones, which frequently harbor co-occurring mutations in epigenetic regulators. Conversely, mutations in signaling genes often occur more than once in distinct subclones, which is consistent with increasing clonal diversity.

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A Harvard-led team reprogrammed DNA methylation patterns of mice with eye problems to restore their sight, AFP reports.

A man in India is suing the Serum Institute of India, saying that he suffered serious side effects from a vaccine it is testing, but the institute has rejected those claims, the Economic Times reports.

The New York Times reports Moderna is planning a clinical trial of its SARS-CoV-2 vaccine in children.

In Nature this week: Readfish tool for targeted nanopore sequencing, genomic diversity of barley and wheat, and more.

Dec
10
Sponsored by
Tecan

CRISPR has developed into a core tool to facilitate genome editing, inspiring transformative ideas in engineering biology. 

Dec
10
Sponsored by
Illumina

Numerous companies now offer non-invasive prenatal screening (testing), many on different technology platforms.