Sigma-Aldrich has launched the Imprint DNA Modification kit, which is based on bisulfite DNA modification technology the company licensed from Epigentek Group, a Brooklyn, NY-based biotechnology company. The new kit completely converts unmethylated cytosine to uracil in less than two hours and requires as little as 50 pg of input DNA. The resulting DNA product is suitable for downstream applications, including qPCR and bisulfite sequencing.
Bioinformatics company CLC bio of Aarhus, Denmark, has released a new software module for Multilocus Sequence Typing. MLST is a portable technique for typing bacteria and yeast isolates. A typical MLST workflow includes assembly, inspection of assembly, trimming of sequence ends, copying and pasting into a web form, and noting the allele number. The new module reduces the time for this workflow from an average 25 minutes to less than a minute, the company said.