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Sigma-Aldrich, CLC bio

Sigma-Aldrich has launched the Imprint DNA Modification kit, which is based on bisulfite DNA modification technology the company licensed from Epigentek Group, a Brooklyn, NY-based biotechnology company. The new kit completely converts unmethylated cytosine to uracil in less than two hours and requires as little as 50 pg of input DNA. The resulting DNA product is suitable for downstream applications, including qPCR and bisulfite sequencing.

Bioinformatics company CLC bio of Aarhus, Denmark, has released a new software module for Multilocus Sequence Typing. MLST is a portable technique for typing bacteria and yeast isolates. A typical MLST workflow includes assembly, inspection of assembly, trimming of sequence ends, copying and pasting into a web form, and noting the allele number. The new module reduces the time for this workflow from an average 25 minutes to less than a minute, the company said.

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.