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SGI, Mitrionics, GenomeQuest, Epicentre, Sigma-Aldrich

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SGI and Mitrionics this week launched a bioinformatics tool based on Field Programmable Gate Array technology and open source software. This product is designed to “break through query logjams” created by next-generation sequencing instruments and multiple-genome studies using NCBI BLAST-n.
 
The new SGI RASC appliance combines SGI’s reconfigurable application-specific computing technology, an accelerated version of Mitrionics’ BLAST-n software, and the SGI Altix server platform for bioinformatics.
 
The companies said the software, whose list price start at $39,950, completes complex BLAST-n queries up to 16 times faster than a standard server based on Intel Itanium 2 processors, and 10 times faster than a server based on AMD Opteron processors.
 

 
GenomeQuest has launched GenomeQuest 4.0, a new, web-enabled platform for genetic sequence data search and analysis, in an attempt to expand beyond its play in gene-patent and -portfolio management information.
 
The new version “encourages” homologous sequence exploration and discloses annotated biochemical and cell signaling information related to sequences of interest. With Web 2.0 architecture and a new application programming interface, GenomeQuest 4.0 supports sequence search application add-ons and web application features such as RSS feeds, tags, mashups, plug-ins, and widgets.
 

 
Epicentre has released its Baseline-ZERO DNase product, which the company said creates cleaner RT-PCR results. The product digests double- and single-stranded DNA to mononucleotides “more effectively” than the commonly used bovine pancreatic DNase I, Epicentre said.
 

 
Sigma-Aldrich this week launched Your Favorite Gene, a new comprehensive, Web-based search tool that matches genes of interest against thousands of Sigma-Aldrich research products.
 
This search engine matches 150,000 shRNAs, 725,000 siRNAs, 4,000 antibodies, proteins, and kits, and 1,000 bioactive small molecules to specific genes of interest.

The Scan

Tens of Millions Saved

The Associated Press writes that vaccines against COVID-19 saved an estimated 20 million lives in their first year.

Supersized Bacterium

NPR reports that researchers have found and characterized a bacterium that is visible to the naked eye.

Also Subvariants

Moderna says its bivalent SARS-CoV-2 vaccine leads to a strong immune response against Omicron subvariants, the Wall Street Journal reports.

Science Papers Present Gene-Edited Mouse Models of Liver Cancer, Hürthle Cell Carcinoma Analysis

In Science this week: a collection of mouse models of primary liver cancer, and more.