By Monica Heger

Cancer has long been known to be a heterogeneous disease, but the extent to which the genomes of cancer cells within a single tumor vary and evolve is just now beginning to be resolved by next-generation sequencing with important implications for therapeutics and diagnosis.

Clonal evolution is "important to cancer biology and important to our understanding of the way we treat cancer," Sam Aparicio of the University of British Columbia and BC Cancer Agency told Clinical Sequencing News.

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Technology Review reports that researchers in the US have used CRISPR to modify a number of human embryos.

By introducing genes from butterfly peas and Canterbury bells, researchers in Japan have developed a blue chrysanthemum, according to NPR.

Plant researchers plan to sequence some 10,000 samples that represent the major plant clades, ScienceInsider reports.

In Nature this week: a Danish reference genome, and more.