Studies published by two independent research teams this past week are extending the scope of sequencing-based analyses applied to cell-free tumor DNA circulating in cancer patients' blood.

Together, the proof-of-principle studies point to the circulating tumor DNA both as a source of information for cataloging the genes and pathways involved in treatment resistance or relapse and as a source of information on metastatic disease in a clinical setting.

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In Science this week: factors influencing retrotransposon integration sites, and more.

A bioethicist argues for the responsible use of germline gene editing.

Some breweries are using DNA-based testing to determine whether unwanted bacteria are affecting their beers, The Verge reports.

Standardized N-of-1 trials will be needed to test out personalized medicines, writes Nicholas Schork from the J. Craig Venter Institute at Nature.