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Funding Update for Jul 13, 2010

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New NIH Grants for Sequencing-Related Technology and Methods, January-June 2010

Project Title: A Novel Method for DNA Fragmentation
Project Start Date: July 1, 2010
Project End Date: March 31, 2012
RFA/PA: PA-09-163
Principal Investigator(s): Jun Hang
Organization: Edge Biosystems
Funding Institute: NHGRI
FY 2010 Funding: $59,380


Project Title: Analysis of Single DNA Polymerase Complexes at 5 Angstrom Precision in Real Time
Project Start Date: July 1, 2010
Project End Date: June 30, 2014
RFA/PA: PA-08-052
Principal Investigator(s): Mark Akeson, Kathy Lieberman
Organization: University of California, Santa Cruz
Funding Institute: NIGMS
FY 2010 Funding: $279,015


Project Title: Analytic Tools to Examine High-Resolution and Genome-Scale Dna Methylation Data
Project Start Date: July 1, 2010
Project End Date: June 30, 2014
RFA/PA: PA-07-070
Principal Investigator(s): Andrew Smith
Organization: University of Southern California
Funding Institute: NHGRI
FY 2010 Funding: $386,696


Project Title: Computational Methods for the Analysis of RNA-seq Data
Project Start Date: July 1, 2010
Project End Date: April 30, 2013
RFA/PA: PA-07-070
Principal Investigator(s): Colin Dewey
Organization: University of Wisconsin, Madison
Funding Institute: NHGRI
FY 2010 Funding: $281,832


Project Title: Development of a Method to Multiplex ChIP-seq and ChIP-chip Experiments
Project Start Date: July 1, 2010
Project End Date: December 31, 2010
RFA/PA: PA-09-080
Principal Investigator(s): Michael Weiner
Organization Affomix
Funding Institute: NHGRI
FY 2010 Funding: $96,738


Project Title: Direct Real-Time Transcriptome Sequencing
Project Start Date: June 15, 2010
Project End Date: March 31, 2012
RFA/PA: RFA-OD-09-008
Principal Investigator(s): Jonas Korlach
Organization: Pacific Biosciences
Funding Institute: NHGRI
FY 2010 Funding: $970,749


Project Title: Acquisition of an Illumina Genome Analyzer System for Functional Genomic Research
Project Start Date: June 10, 2010
Project End Date: June 9, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Rui Chen
Organization: Baylor College of Medicine
Funding Institute: NCRR
FY 2010 Funding: $500,000


Project Title: Genome Sequencer FLX Instrument
Project Start Date: June 10, 2010
Project End Date: June 9, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Anne Kane
Organization: Tufts Medical Center
Funding Institute: NCRR
FY 2010 Funding: $493,500


Project Title: Attomole-Level High-Throughput Genomics
Project Start Date: June 9, 2010
Project End Date: Nov. 30, 2010
RFA/PA: PA-09-080
Principal Investigator(s): Patrice Milos
Organization: Helicos BioSciences
Funding Institute: NHGRI
FY 2010 Funding: $146,400


Project Title: Uniform Length DNA for Paired-End Nextgen Sequencing via In Vitro Packaging
Project Start Date: June 4, 2010
Project End Date: Nov. 30, 2010
RFA/PA: PA-09-080
Principal Investigator(s): Frederick Blattner
Organization: Scarab Genomics
Funding Institute: NIAID
FY 2010 Funding: $127,387


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Project Title: Custom Oligonucleotide Libraries Synthesis
Project Start Date: June 1, 2010
Project End Date: May 31, 2011
RFA/PA: PA-09-080
Principal Investigator(s): Jean-Marie Rouillard
Organization: BioDiscovery
Funding Institute: NIGMS
FY 2010 Funding: $214,713


Project Title: Methods for the Analysis and Integration of Next-Generation Sequencing with Appl[ications in Epigenomics]
Project Start Date: June 1, 2010
Project End Date: Feb. 28, 2015
RFA/PA: PA-07-458
Principal Investigator(s): William Johnson
Organization: Brigham Young University
Funding Institute: NHGRI
FY 2010 Funding: $349,700


Project Title: Developing Novel Deep Sequencing Techniques for Studying HIV Evolution
Project Start Date: May 27, 2010
Project End Date: May 26, 2012
RFA/PA: PA-09-210
Principal Investigator(s): Stephanie Willerth
Organization: University of California, Berkeley
Funding Institute: NIDA
FY 2010 Funding: $47,606


Project Title: Applied Biosystems SOLiD 3 System
Project Start Date: May 20, 2010
Project End Date: May 19, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Howard Edenberg
Organization: Indiana University-Purdue University at Indianapolis
Funding Institute: NCRR
FY 2010 Funding" $492,387


Project Title: Pseudo-Complementary DNA
Project Start Date: May 14, 2010
Project End Date: Feb. 29, 2012
RFA/PA: PA-09-164
Principal Investigator(s): Howard Gamper
Organization: Thomas Jefferson University
Funding Institute: NHGRI
FY 2010 Funding: $231,750


Project Title: Expanding Data Collection via High-Throughput DNA Sequencing
Project Start Date: May 6, 2010
Project End Date: May 5, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Stephan Schuster
Organization: Pennsylvania State University
Funding Institute: NCRR
FY 2010 Funding: $499,800


Project Title: Illumina Genome Analyzer II
Project Start Date: May 6, 2010
Project End Date: May 5, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Dirk Bohmann
Organization: University of Rochester
Funding Institute: NCRR
FY 2010 Funding: $499,800


Project Title: Illumina Genome Analyzer II
Project Start Date: April 29, 2010
Project End Date: April 28, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Deborah Nickerson
Organization University of Washington
Funding Institute NCRR
FY 2010 Funding $500,000


Project Title: Illumina Genome Analyzer II (GAII) (110V/220V)
Project Start Date: April 22, 2010
Project End Date: April 21, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Kevin White
Organization: University of Chicago
Funding Institute: NCRR
FY 2010 Funding: $470,000


Project Title: Acquisition of a SOLiD 3 Sequencer
Project Start Date: April 15, 2010
Project End Date: April 14, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Scott Keeney, Eric Lai, Samuel Singer, Agnes Viale
Organization: Sloan-Kettering Institute for Cancer Research
Funding Institute: NCRR
FY 2010 Funding: $425,000


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Project Title: Core Research Computing Facility
Project Start Date: April 15, 2010
Project End Date: April 14, 2013
RFA/PA: RFA-RR-09-007
Principal Investigator(s): David Hirsh
Organization: Columbia University
Funding Institute: NCRR
FY 2010 Funding: $9,963,289


Project Title: Directed Evolution of RNA Ligases for High-Throughput Sequencing
Project Start Date: April 15, 2010
Project End Date: March 31, 2012
RFA/PA: PA-07-459
Principal Investigator(s): Andrew Ellington
Organization University of Texas, Austin
Funding Institute: NHGRI
FY 2010 Funding: $223,840


Project Title: Genome Sequencer FLX
Project Start Date: April 15, 2010
Project End Date: April 14, 2011
RFA/PA: PAR-09-118
Principal Investigator(s): John Ngai
Organization: University of California, Berkeley
Funding Institute: NCRR
FY 2010 Funding: $622,934


Project Title: High Performance Sample Preparation Instrument
Project Start Date: April 15, 2010
Project End Date: April 14, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Andres Maricq
Organization: University of Utah
Funding Institute: NCRR
FY 2010 Funding: $122,000


Project Title: Illumina Genome Analyzer IIx "Next Generation" DNA Sequencer
Project Start Date: April 15, 2010
Project End Date: April 14, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): John Quackenbush
Organization: Dana-Farber Cancer Institute
Funding Institute: NCRR
FY 2010 Funding: $390,000


Project Title: UNMC SIG Supporting Next-Generation DNA Sequencing Technology
Project Start Date: April 15, 2010
Project End Date: April 14, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): James Eudy
Organization University of Nebraska Medical Center
Funding Institute: NCRR
FY 2010 Funding: $500,000


Project Title: Advanced DNA Sequencing and Computing Resources in Support of NIH-Funded Research
Project Start Date: April 8, 2010
Project End Date: April 7, 2011
RFA/PA: PAR-09-118
Principal Investigator(s): Glenn Hicks
Organization: University of California, Riverside
Funding Institute: NCRR
FY 2010 Funding: $742,627


Project Title: An Integrated System for Deep Sequencing Experiment and Analysis
Project Start Date: April 8, 2010
Project End Date: April 7, 2011
RFA/PA: PAR-09-118
Principal Investigator(s): Bin Tian
Organization: University of Medicine and Dentistry of New Jersey —- New Jersey Medical School
Funding Institute: NCRR
FY 2010 Funding: $498,750


Project Title: Illumina Genome Analyzer IIx
Project Start Date: April 8, 2010
Project End Date: April 7, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Norma Nowak
Organization: State University of New York at Buffalo
Funding Institute: NCRR
FY 2010 Funding: $499,800


Project Title: Illumina Genome Analyzer IIx
Project Start Date: April 8, 2010
Project End Date: April 7, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Richard Young
Organization: Whitehead Institute for Biomedical Research
Funding Institute: NCRR
FY 2010 Funding: $499,968


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Project Title: True Direct Single Molecule RNA Sequencing
Project Start Date: April 1, 2010
Project End Date: Feb. 28, 2013
RFA/PA: PA-07-458
Principal Investigator(s): Patrice Milos
Organization: Helicos BioSciences
Funding Institute: NHGRI
FY 2010 Funding: $528,500


Project Title: Illumina Genome Analyzer IIx (GA-IIx) High-Throughput Sequencing (HTS) System
Project Start Date: March 31, 2010
Project End Date: March 30, 2011
RFA/PA: PAR-09-118
Principal Investigator(s): Robert Burgess
Organization: Jackson Laboratory
Funding Institute: NCRR
FY 2010 Funding: $543,171


Project Title: Roche 454 Next Generation Sequencer for Human Microbiome and Infectious Disease Research
Project Start Date: March 25, 2010
Project End Date: March 24, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Jane Carlton
Organization: New York University School of Medicine
Funding Institute: NCRR
FY 2010 Funding: $485,500


Project Title: Acquisition of an Illumina Genome Analyzer for the Research Institute at Nationwide Children's Hospital
Project Start Date: March 18, 2010
Project End Date: March 17, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Peter White
Organization: Research Institute at Nationwide Children's Hospital
Funding Institute: NCRR
FY 2010 Funding: $500,000


Project Title: Roche 454 GS FLX DNA Sequencer
Project Start Date: March 18, 2010
Project End Date: March 17, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): William Farmerie
Organization: University of Florida
Funding Institute: NCRR
FY 2010 Funding: $500,000


Project Title: Shared High-Throughput DNA Sequencer for the Brown University Community
Project Start Date: March 18, 2010
Project End Date: March 17, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Gary Wessel
Organization: Brown University
Funding Institute: NCRR
FY 2010 Funding: $499,800


Project Title: Biomedical Genomics Center: Next-Generation Sequencing Instrumentation
Project Start Date: March 11, 2010
Project End Date: March 10, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Kenneth Beckman
Organization: University of Minnesota Twin Cities
Funding Institute: NCRR
FY 2010 Funding: $500,000


Project Title: Implementation of Innovative RNA Sample Quality Control Methods
Project Start Date: March 11, 2010
Project End Date: Feb. 28, 2012
RFA/PA: RFA-CA-09-004
Principal Investigator(s): John Anders, Tanya Kanigan, James Willey
Organization: University of Toledo Health Science Campus
Funding Institute: NCI
FY 2010 Funding: $194,432


Project Title: Next Generation Sequencer
Project Start Date: March 11, 2010
Project End Date: March 10, 2011
RFA/PA PAR-09-028
Principal Investigator(s): Charis Eng
Organization: Cleveland Clinic
Funding Institute: NCRR
FY 2010 Funding: $500,000


Project Title: High Definition Clonal Analyses of Archival Pancreatic Adenocarcinoma Samples
Project Start Date: March 1, 2010
Project End Date: Feb. 28, 2013
RFA/PA: RFA-CA-09-008
Principal Investigator(s): Michael Barrett
Organization: Translational Genomics Research Institute
Funding Institute: NCI
FY 2010 Funding: $257,303


Project Title: Automated Nucleic Acid Extractor System: Autogenflex Star/Autogen Quick-Gene 810
Project Start Date: Feb. 20, 2010
Project End Date: Feb. 19, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Kenneth Cornetta
Organization Indiana University-Purdue University at Indianapolis
Funding Institute: NCRR
FY 2010 Funding: $159,460


Project Title: Illumina Genome Analyzer IIx for UMass Deep Sequencing Core
Project Start Date: Feb. 18, 2010
Project End Date: Feb. 17, 2011
RFA/PA: PAR-09-028
Principal Investigator(s): Scot Wolfe
Organization: University of Massachusetts Medical School, Worcester
Funding Institute: NCRR
FY 2010 Funding: $489,250


Project Title: Rational Engineering of Nanopost Arrays for DNA Electrophoresis
Project Start Date: Feb. 1, 2010
Project End Date: Jan. 31, 2013
RFA/PA: PA-07-070
Principal Investigator(s): Kevin Dorfman
Organization: University of Minnesota Twin Cities
Funding Institute: NHGRI
FY 2010 Funding: $281,522

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