By Bernadette Toner

Researchers at the Scripps Translational Science Institute are investigating a range of technical issues involved in using next-generation sequencing to help guide therapy for cancer patients — including the pros and cons of exome sequencing over whole-genome sequencing, as well as the impact of tumor heterogeneity on sequencing results.

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In PNAS this week: genomic study of group B Streptococcus evolution, selection on the X chromosome in great apes, and more.

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