By Monica Heger

This story was originally published Jan. 5.

Next-gen sequencing could find a new application in synthetic biology — as a sample-prep step to make DNA for gene synthesis. Scientists from the German company Febit are looking to spin out a new company that would commercialize a new method of DNA synthesis based on the approach, which they say could reduce the price of synthetic DNA by several fold.

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In Science this week: factors influencing retrotransposon integration sites, and more.

A bioethicist argues for the responsible use of germline gene editing.

Some breweries are using DNA-based testing to determine whether unwanted bacteria are affecting their beers, The Verge reports.

Standardized N-of-1 trials will be needed to test out personalized medicines, writes Nicholas Schork from the J. Craig Venter Institute at Nature.