Researchers at the Wellcome Trust Sanger Institute have demonstrated that it is possible to sequence DNA on the Pacific Biosciences RS without first doing library preparation. They achieved the best results when the DNA was circular, but found that they could directly sequence linear DNA as well.

Senior author Harold Swerdlow told In Sequence that because the method requires no sample prep and works with limited DNA it could have applications in outbreak scenarios, acute disease detection, metagenomics, and forensics.

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An Australian-led team has generated a draft genome assembly of the invasive cane toad in hopes it will help in population control, the Sydney Morning Herald reports.

The New York Times reports that the US Department of Defense has implemented about half the recommendations made to improve safe handling of dangerous agents.

In PLOS this week: approach for teasing out archaic introgression in human genomes, immune transcription features in HCV infection, and more.

Stat News reports that Maryland is promoting itself to the biotech industry with a mobile billboard.